Part of this Programme
Level of Qualification|Semesters|ECTS
Bachelor | Semestral | 5
Year | Type of course unit | Language
1 |Mandatory |Português
Total of Working Hours | Duration of Contact (hours)
125 | 60
Recommended complementary curricular units
Prerequisites and co-requisites
The living cell; Prokaryotic and eukaryotic cells. Constitution of the cell. The genetic material. Proteins; lipids and polysaccharides. The central tenet of molecular biology. Replication, transcription and translation. Organelles and cellular structures: Cytoskeleton - cytoplasmic organization. Mechanisms of muscle contraction. Cell membrane - functional boundary of the cell. Membrane transport. Endomembranous system - processing and distribution of biomolecules. Endoplasmic reticulum and Golgi apparatus. Exocytosis and endocytosis. Lysosome - the digestive center of the cell. Nutrition, defense, autophagy, autolysis and extracellular digestion. Peroxisome - detoxification center. Mitochondria and Chloroplast - bioenergetic centers. Respiratory function and photosynthetic function. Biology of Nucleus and Chromatin. Levels of chromatin organization. Structural and functional compartmentalization. Processes and regulation. Cell death: necrosis and apoptosis
Ability to have a global perspective on the functioning of cells and consequently of the organism itself. The main objective is to understand the cellular and molecular events related to cell regulation and differentiation. Ability to perform laboratory work under microscopy, vital coloration, functional and quantitative studies, with rigor and safety.
Knowledge, abilities and skills to be acquired
The student will be able to identify the animal and plant cell, understand the importance of cellular architecture in the functioning of the cell as structuring entity of all living beings. The student will still be able to understand the different techniques of cell biology and its application in scientific research
Teaching methodologies and assessment
The discipline of Cell Biology is composed of a theoretical component and a practical component. Theoretical component is taught through Powerpoint presentations on the topics included in the syllabus. The evaluation consists of the approval in the theoretical component for realizing two frequencies or a final exam and the laboratory component for the reports on the subjects studied in the classes and two practical tests on the subject. Note of the theoretical component (60% of final grade): Frequency 1 + Frequency 2 (there is no minimum grade at each frequency, final grade = average of 2 frequencies10) or Final exam (1st or 2nd call) of final grade): Six reports (40% practical grade) + Two practical tests (60% practical grade) The final approval depends on obtaining a classification above 10 values in the practical classes and in the theoretical or average exam of the frequencies. Approval is required in practice to take the theoretical exam.
- Azevedo, C., Sunkel, C. E. (2012).Biologia Celular e Molecular, Liddel ¿ (5º Edição) Edições Técnicas, Lisboa
- Lodish, H., Berk, A., Zipursky, S. L., Matsudaira, P., Baltimore, D., Darnel, J. (2004) Molecular Cell Biology, 5E d, W. H. Freeman and Company, New York.
- Alberts, B., Jonhson, A., Lewis, J. , Raff, M., Roberts, K., Walter, P. (2002) Molecular Biology of the Cell, 4Ed., Garland Publishing, New York.
- Cooper, G.M. and Hau sman, R.E. (2007)The Cell, A molecular approach 4Ed, Sinauer Associates, Washington, DC,USA
- Bec ker, W.M., Kleinsmith, L.J., Hardin, J. (2005). The World of the Cell (6th ed.). Benjamin Cummings Publ. Co.