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Universidade Lusófona



Pharmaceutical Sciences

Level of Qualification|Semesters|ECTS

Bachelor; Master | Semestral | 4

Year | Type of course unit | Language

3 |Mandatory |Português

Total of Working Hours | Duration of Contact (hours)

110 | 60



Recommended complementary curricular units


Prerequisites and co-requisites




Professional Internship



1. Introduction to Immunology ¿ antigens
2. Cells and organs of the Immune System Hematopoiese
- Cells of the immune System
- Lymphoid cells
- B Lymphocytes
- T Lymphocytes
- Primary limphoid organs
- Secondary limphoid organs
3. Immunoglobulins
- Structure
- Diversity
- Variability
4. Major Histocompatibility Complex
- Genes and mollecules of the MHC
- Antigen procesing and presentation
5. T cell receptor (TCR)
6. T cell activation and differentiation
7. B cell activation and differentiation
8. Citokynes
- Structure and function
- Regulation
9. The Complement System
- Activation and regulation
10. Inflamatory response
11. Hipersensitivity reactions
12. Immune Adverse Drug Reactions
13. Immune system in health and disease
- Infectious diseases
- Allergic diseases
- Vacines
- Immunodeficiencies
- Autoimunity
- Tumoral immunity


After attending this CU, the student should know the structure organization and function of the immune system. Students will know how the immune system works in order to understand physiologic and pathologic immune responses.

Knowledge, abilities and skills to be acquired

The knowledge of the interaction between innate and acquired immunity and regulation mechanisms are important steps to understand reaction to antigens, namely drug antigens.
The laboratory classes allow students to manipulate and analyse components of the immune system. Autonomy, organization, responsibility and group cooperation are promoted in the laboratory.

Teaching methodologies and assessment

The teaching methodologies include various instruments based on attending classes (lectures/tutorial) and on other non-attending resources (eg moodle). In the tutorial component the fundamental topics of the syllabus are explored in more detail, through the execution of laboratory assays that allow the consolidation of the subjects lectured.

Evaluation: a minimum of 9.5 values is required for approval to the CU.
A) Continuous evaluation ¿ including the following components:
¿ Two written tests covering the entire syllabus (T1 and T2) - 25%
¿ Practical classes performance ¿ 20% (A)

Final grade = T1(40%) + T2(40%) + A(20%)

B) Exam and grade improvement exam
¿ Evaluation by final exam covering the entire syllabus (written and experimental exam).


Arosa, F.A., Cardoso, E.M., Pacheco, F.C. (2014) Fundamentos de Imunologia (2º ed) Lidel
2. Goldsby, R.A. et al.(2013), Kuby Immunology, 7th Ed., New York, W.H. Freeman & Company Eds,
3. Abbas, A.K., Lichtman, A.H.(2012), Cellular and Molecular Immunology, 7th Ed., Elsevier / Saunders
4. Janeway, C.A. et al, Immunobiology (2011), 8th Ed., Garland Science