Class Cellular and Molecular Biology I

The student will be able to identify the animal and plant cell, understand the importance of cellular architecture in cell functioning as a structuring entity of all living beings. The student will also be able to understand the different techniques of cell biology and its application in scientific research.

1. The living cell, prokaryotic and eukaryotic cells. Constitution of the cell. The genetic material. Proteins, lipids, and carbohydrates.

2. Introduction to cellular genetics: The central dogma of molecular biology. Replication, transcription, and translation.

3. Organelles and cellular structures: - Cytoskeleton: cytoplasmic organization. Cell membrane: Biological barrier. Membrane transport. - System endomembranous: processing and distribution of biomolecules. Endoplasmic reticulum and Golgi apparatus. Exocytosis and endocytosis. ¿ Lysosome: cell's digestion of macromolecules. Nutrition, defense, autophagy, autolysis and extracellular digestion. ¿ Peroxisomes: catabolic center. - Mitochondria and Chloroplast: bioenergy. Respiratory and photosynthetic function. - Biology of the Nucleus and Chromatin. Organization levels of chromatin. Functional and structural compartmentalization

4. Cell Cycle. Main processes and regulation. Cell death: necrosis and apoptosis

Development of educational strategies that make the connection between theory and practice in order to develop students' critical spirit

- Azevedo, C., Sunkel, C.E. (2012).Biologia Celular e Molecular, Liddel ¿ (5º Edição) Edições Técnicas, Lisboa

- Lodish, H., Berk, A., Zipursky, S. L., Matsudaira, P., Baltimore, D., Darnel, J. (2004) Molecular Cell Biology, 5Ed, W. H.

Freeman and Company, New York.

- Alberts, B., Jonhson, A., Lewis, J., Raff, M., Roberts, K., Walter, P. (2002) Molecular Biology of the Cell, 4Ed., Garland

Publishing, New York.

- Cooper, G.M. and Hausman, R.E. (2007)The Cell, A molecular approach 4Ed, Sinauer Associates, Washington, DC,

USA

- Becker, W.M., Kleinsmith, L.J., Hardin, J. (2005). The World of the Cell (6th ed.). Benjamin Cummings Publ. Co.