Class Cell Biology

This UC introduces the constitution, structure and funcion of the cell as a functional unit but also as part of multicelular organisms.

1. The cell 
   1. Cell theory
   2. Chemical composition
   3. Prokaryotic and eukaryotic cells
   4. Transport mechanisms
2. Organelles and cellular structures ¿ structure/function relationship 
   1. Biological membranes
   2. Nucleus
   3. ER, RER and Golgi complex
   4. Mitochondria
   5. Chloroplast
   6. Cytoskeleton
   7. ECM
3. Intercellular communication and adhesion  
   1. Cell-cell and cell-substrate adhesion
   2. Signalling pathways
4. Genome 
   1. Central dogma of Biology
   2. Different condensation states of chromatin
   3. Prokaryotic versus eukaryotic genome
   4. Gene
5. Replication, transcription and translation  
   1. DNA replication mechanism, replication fork, DNA polymerases
   2. Transcription mechanism, RNA polymerases
   3. Transcript processing
   4. Genetic code
   5. tRNAs and ribosome
   6. Polypeptide chain production
6. Gene expression regulation 
   1. Why regulate gene expression?
   2. Cell differentiation
7. Cell cycle 
   1. Mitosis and meiosis
   2. Cell cycle control
   3. Apoptosis

Active learning methodologies based on the resolution of practical problems, on the exposition by the students of some concepts addressed in laboratory classes and the use of observations/results obtained in the laboratory as a starting point for the discussion of more complex concepts/topics.

• Lodish, H et al. (2012), Molecular Cell Biology, 7^th  Ed, W. H. Freeman and Co. (Informação complementar online: http://bcs.whfreeman.com/lodish7e/#t_800911____)
• Reece, J. B, Urry, L. A., Cain, L. C., Wasserman, S. A., Minorsky, P. V., Jackson, R.B., (2013) Campbell Biology, 10^th ed., Pearson Education, Inc.
• Campos, L.S. (2008); Entender a Bioquímica, 5ªed. Escolar Editora.