filmeu

Docente
Patrícia Dias Mendonça Rijo

Patrícia Dias Mendonça Rijo
pat***@ulusofona.pt
851A-88C2-0D45
0000-0001-7992-8343

Resume

Patrícia Rijo has a degree in Chemistry from the Faculty of Sciences of the University of Lisbon (FCUL), and a Master and Ph.D. in Pharmaceutical and Therapeutic Chemistry from the Faculty of Pharmacy of the University of Lisbon (FFUL). She is currently an Associate Professor at the School of Health Sciences and Technologies (ECTS) at Universidade Lusófona (ULHT, Lisbon, Portugal) where she is responsible for Organic Medicinal Chemistry and Pharmacognosy and the international coordinator. The main area of research is medicinal chemistry, phytochemistry, and pharmacognosy, with an emphasis on the Chemistry of Natural Products. She is the director of Research and Innovation at CBIOS (Research Center for Biosciences and Health Technologies at Universidade Lusófona), where she leads the Laboratory of Natural Bioactives (Bio.Natural). She has participated since 2015, in 7 international scientific networks (COST Action and CYTED) and she is currently vice-chair of the COST action CA21145 and has participated in international project evaluation juries (EU, Serbia, Argentina, Chile and France - Agence National de la recherche) in the area of Medicinal Chemistry, specifically in Chemistry of Natural Products. Patrica has been actively engaged in societal enrichment through various University Extension activities, focusing on science outreach, communication, and dissemination. Spearheading initiatives such as the 'New European Bauhaus' and 'CiênciaVitae - CBIOS,' she has coordinated 14 science outreach projects and orchestrated 23 national and international scientific events. Noteworthy engagements include participation in the 'Talent Bootcamp FCT NOVA and FCUL' and events like the -Global Women s Breakfast- organized by IUPAC. Since 2019, she has the privilege of presiding over the Bio.Natural-Bioactive Natural Products Research Meeting. Patricia Rijo is associate editor of Phytomedicine (Elsevier) and Frontiers in Pharmacology, (specialty section of Ethnopharmacology and Drug Discovery) and Editorial board of -Pharmaceuticals-, Natural Products section, MDPI. Patrícia has published more than 140 articles in international peer-review journals, she is in the - World's Top 2% Scientists list - from Stanford University in 2022 and 2023, and has more than 300 communications (oral and panel) presented at national and international meetings and conferences, and has three registered patents.

Graus

  • Mestrado
    Química Farmacêutica
  • Licenciatura
    Química
  • Doutoramento
    Farmácia

Publicações

Artigo em revista

  • 2024-10, Antibiotic coordination frameworks (ACFs) against antibiotic resistance - How to involve students through experimental practices in the search for solutions to public health problems, Journal of Chemical Education
  • 2024-06, Reactivity of 7a-acetoxy-6ß-hydroxyroyleanone and ability of its derivatives to modulate PKC isoform, Scientific Reports
  • 2024-05, Biological activity of 6, 7-dehydroroyleanone and derivatives obtained from Plectranthus aliciae (Codd) A.J.Paton., ACS Omega
  • 2024-03-15, Anticancer Diterpenes of African Natural Products: Current Advances in Cancer Treatment, Phytomedicine
  • 2024-02-16, Enhancement of Vitamin C’s Protective Effect against Thimerosal-Induced Neurotoxicity in the Cerebral Cortex of Wistar Albino Rats: An In Vivo and Computational Study, ACS Omega
  • 2024-01-25, Synergistic Differential DNA Demethylation Activity of Danshensu (Salvia miltiorrhiza) Associated with Different Probiotics in Nonalcoholic Fatty Liver Disease, Biomedicines
  • 2023-12-25, Nature’s Green Potential: Anticancer Properties of Plants of the Euphorbiaceae Family, Cancers
  • 2023-11-23, Hybrid azole-based conjugates as upcoming anticancer and antimicrobial agents, Exploration of Drug Science
  • 2023-10-24, Drug Development Inspired by Natural Products II, Molecules
  • 2023-07-12, Coleon U, Isolated from Plectranthus mutabilis Codd., Decreases P-Glycoprotein Activity Due to Mitochondrial Inhibition, Pharmaceutics
  • 2023-06, Distinctive Azole-based Conjugates as Potential Anticancer and Antimicrobial Agents: A Preliminary Biological Survey, Journal of Heterocyclic Chemistry
  • 2023-05-22, Application of Rosmarinic Acid with Its Derivatives in the Treatment of Microbial Pathogens, Molecules
  • 2023-03-09, In Vitro Photoprotection and Functional Photostability of Sunscreen Lipsticks Containing Inorganic Active Compounds, Cosmetics
  • 2023-03, Counteracting Colon Cancer by Inhibiting Mitochondrial Respiration and Glycolysis with a Selective PKCd Activator, International Journal of Molecular Sciences
  • 2023-02-03, Inactivation of Escherichia coli in an Orange Juice Beverage by Combined Ultrasonic and Microwave Treatment, Foods
  • 2023-01, Eco-friendly fabricated multibioactive Ca(II)-antibiotic coordination framework coating on zinc towards improved bone tissue regeneration, Colloids and Surfaces B: Biointerfaces
  • 2023, Evaluation of the Lysyl Oxidase-Like 2 (LOXL2) inhibitory activity of pimaranes and their glycosyl derivatives, Journal Biomedical and Biopharmaceutical Research
  • 2022-12-12, Rosmarinic Acid Multifunctional Sunscreen: Comet Assay and In Vivo Establishment of Cutaneous Attributes, Cosmetics
  • 2022-11-30, Celosia trigyna Linn (Cucurbitaceae) Annihilate Human Breast, Colon, and Lung Cancer Cells: Combination of Cheap Template for Anticancer Screening, International Journal of Translational Medicine
  • 2022-11-23, Dehydroroyleanone as a Building Block for a Drug Delivery Platform Based on Self-Assembled Nanoparticles: Structural Studies and Chemical Modification, ACS Omega
  • 2022-11-01, Effect of Sonication on Microwave Inactivation Kinetics of Enterococcus faecalis in Dairy Effluent, Molecules
  • 2022-10-23, Kefir and the Gut–Skin Axis, International Journal of Environmental Research and Public Health
  • 2022-10-15, An Evaluation of the Novel Biological Properties of Diterpenes Isolated from Plectranthus ornatus Codd. In Vitro and In Silico, Cells
  • 2022-10, Parvifloron D-based potential therapy for glioblastoma: Inducing apoptosis via the mitochondria dependent pathway, Frontiers in Pharmacology
  • 2022-10, Lethality Bioassay using Artemia salina L., Journal of visualized experiments : JoVE
  • 2022-10, Anticancer Properties of Plectranthus ornatus-Derived Phytochemicals Inducing Apoptosis via Mitochondrial Pathway, International Journal of Molecular Sciences
  • 2022-08-23, Low Platinum-Content Electrocatalysts for Highly Sensitive Detection of Endogenously Released H2O2, Biosensors
  • 2022-07-19, The Impact of Kefir on Epidermal Water Homeostasis in Healthy Human Skin, Life
  • 2022-07, Ionic exchange membranes in the pharmaceutical industry – Review, Journal Biomedical and Biopharmaceutical Research
  • 2022-06-14, Phytochemical Study and Antiglioblastoma Activity Assessment of Plectranthus hadiensis (Forssk.) Schweinf. ex Sprenger var. hadiensis Stems, Molecules
  • 2022-06-02, Azadirachta indica (Neem) as a Potential Natural Active for Dermocosmetic and Topical Products: A Narrative Review, Cosmetics
  • 2022-05, Characterization of lipid extracts from the Hermetia illucens larvae and their bioactivities for potential use as pharmaceutical and cosmetic ingredients., Heliyon
  • 2022-04-26, Enhanced Anticancer Activity of Hymenocardia acida Stem Bark Extract Loaded into PLGA Nanoparticles, Pharmaceuticals
  • 2022-04-14, C20-nor-Abietane and Three Abietane Diterpenoids from Plectranthus mutabilis Leaves as P-Glycoprotein Modulators, ACS Medicinal Chemistry Letters
  • 2022-03-11, Hidden in Plants—A Review of the Anticancer Potential of the Solanaceae Family in In Vitro and In Vivo Studies, Cancers
  • 2022-01-09, Microalgae as a Sustainable, Natural-Oriented and Vegan Dermocosmetic Bioactive Ingredient: The Case of Neochloris oleoabundans, Cosmetics
  • 2022-01, Silver(I)-Tazobactam Frameworks with Improved Antimicrobial Activity, Frontiers in Chemistry
  • 2022, Parvifloron D-based therapy for glioblastoma: targeting tumor microenvironment with a natural drug lead, European Journal of Clinical Investigation
  • 2021-12-31, Rapid UV-Vis spectroscopy methods for quantification of ranitidine tablets, Journal Biomedical and Biopharmaceutical Research
  • 2021-12-26, An overview of violence and sexual abuse in children: global data, policy responses, and multidisciplinary approaches in health care, Journal Biomedical and Biopharmaceutical Research
  • 2021-11-13, Homemade Kefir Consumption Improves Skin Condition—A Study Conducted in Healthy and Atopic Volunteers, Foods
  • 2021-11-04, Probiotics in the gut-skin axis – the case of kefir, Journal Biomedical and Biopharmaceutical Research
  • 2021-11, Plectranthus ecklonii Benth: A Comprehensive Review Into its Phytochemistry and Exerted Biological Activities, Frontiers in Pharmacology
  • 2021-09, Self-Assembly Nanoparticles of Natural Bioactive Abietane Diterpenes, International Journal of Molecular Sciences
  • 2021-06-02, Dehydroabietic Acid Microencapsulation Potential as Biofilm-Mediated Infections Treatment, Pharmaceutics
  • 2021-06, General Toxicity screening of Royleanone derivatives using an Artemia salina model, Journal Biomedical and Biopharmaceutical Research
  • 2021-05-18, Preliminary Phytochemical Analysis and Evaluation of the Biological Activity of Leonotis nepetifolia (L.) R. Br Transformed Roots Extracts Obtained through Rhizobium rhizogenes-Mediated Transformation, Cells
  • 2021-05-15, A Newfangled Collagenase Inhibitor Topical Formulation Based on Ethosomes with Sambucus nigra L. Extract, Pharmaceuticals
  • 2021-05-13, Characterizing the Mechanism of Action of Essential Oils on Skin Homeostasis—Data from Sonographic Imaging, Epidermal Water Dynamics, and Skin Biomechanics, Cosmetics
  • 2021-05, Characterization of Kefir Produced in Household Conditions: Physicochemical and Nutritional Profile, and Storage Stability, Foods
  • 2021-04-23, Preliminary Biological Activity Screening of Plectranthus spp. Extracts for the Search of Anticancer Lead Molecules, Pharmaceuticals
  • 2021-04, Acceptability of kefir produced by fermentation of Portuguese milk with CIDCA AGK1 grains in a sample of Portuguese consumers, Biomedical and Biopharmaceutical Research Journal
  • 2021-03-28, Antimicrobial Activity of Pyrazinamide Coordination Frameworks Synthesized by Mechanochemistry, Molecules
  • 2021-03-11, Antimicrobial Ceramic Filters for Water Bio-Decontamination, Coatings
  • 2021-02-19, LOXL2 Inhibitors and Breast Cancer Progression, Antioxidants
  • 2021-01-01, Screening the dermatological potential of plectranthus species components: antioxidant and inhibitory capacities over elastase, collagenase and tyrosinase, Journal of Enzyme Inhibition and Medicinal Chemistry
  • 2021, Roots and rhizomes of wild Asparagus: Nutritional composition, bioactivity and nanoencapsulation of the most potent extract, Food Bioscience
  • 2021, Rebound increases in chemokines by CXCR2 antagonist in breast cancer can be prevented by PKCd and PKCe activators, Cytokine
  • 2021, Functionalized Cyclopentenones and an Oxime Ether as Antimicrobial Agents, ChemMedChem
  • 2021, Enhanced Accumulation of Betulinic Acid in Transgenic Hairy Roots of Senna obtusifolia Growing in the Sprinkle Bioreactor and Evaluation of Their Biological Properties in Various Biological Models, Chemistry and Biodiversity
  • 2021, Editorial: “Natural Products as a Tool to Design New anti-MDR Lead Molecules.”, Frontiers in Pharmacology
  • 2021, Design and synthesis of naphthylchalcones as novel anti-leukaemia agents, Bioorganic Chemistry
  • 2021, Avaliação da toxicidade geral de derivados de Roileanonas pelo ensaio de letalidade de Artemia salina
  • 2020-11-30, Phytochemical and Pharmacological Study of Plectranthus ecklonii Benth, Proceedings
  • 2020-11-29, Grape Pomace: A Potential Ingredient for the Human Diet, Foods
  • 2020-11-14, Development of New Catalytic Material for Accurate Detection of Biological Biomarkers Related to Most Common Non-Communicable Diseases, Proceedings
  • 2020-11, Royleanone Derivatives From Plectranthus spp. as a Novel Class of P-Glycoprotein Inhibitors, Frontiers in Pharmacology
  • 2020-11, Preliminary evaluation of the antimicrobial activity of different Hermetia illucens larvae extracts for application as a cosmetic ingredient, Biomedical and Biopharmaceutical Research Journal
  • 2020-09-16, In Vitro Antimicrobial Activity of Isopimarane-Type Diterpenoids, Molecules
  • 2020-09-10, Biomolecules and Electrochemical Tools in Chronic Non-Communicable Disease Surveillance: A Systematic Review, Biosensors
  • 2020-06-30, Unveiling the Mechanism of Action of 7a-acetoxy-6ß-hydroxyroyleanone on an MRSA/VISA Strain: Membrane and Cell Wall Interactions, Biomolecules
  • 2020-06-29, Bioactive Compounds from Hermetia Illucens Larvae as Natural Ingredients for Cosmetic Application, Biomolecules
  • 2020-06-16, Diterpenoids from Plectranthus spp. as Potential Chemotherapeutic Agents via Apoptosis, Pharmaceuticals
  • 2020-06-10, Assessment of the Potential Skin Application of Plectranthus ecklonii Benth., Pharmaceuticals
  • 2020-06-03, Natural Products: Optimizing Cancer Treatment through Modulation of Redox Balance, Oxidative Medicine and Cellular Longevity
  • 2020-05-26, Zoopharmacology: A Way to Discover New Cancer Treatments, Biomolecules
  • 2020-05-23, Activity to Breast Cancer Cell Lines of Different Malignancy and Predicted Interaction with Protein Kinase C Isoforms of Royleanones, International Journal of Molecular Sciences
  • 2020-05-20, Bioactivity of Isostructural Hydrogen Bonding Frameworks Built from Pipemidic Acid Metal Complexes, Molecules
  • 2020-04-06, Artemia species: An important tool to screen general toxicity samples, Current Pharmaceutical Design
  • 2020-04, III Lusófona¿s Nutrition Meeting, Biomedical and Biopharmaceutical Research Journal
  • 2020-03, Molecular Docking Studies of Royleanone Diterpenoids from Plectranthus spp. as P-Glycoprotein Inhibitors, ACS Medicinal Chemistry Letters
  • 2020-01-30, Green extraction of Sambucus nigra L. for potential application in skin nanocarriers, Green Materials
  • 2020-01-19, Anti-Migratory and Pro-Apoptotic Properties of Parvifloron D on Triple-Negative Breast Cancer Cells, Biomolecules
  • 2020, Preliminary evaluation of the antimicrobial activity of different Hermetia illucens larvae extracts for application as a cosmetic ingredient,Avaliação preliminar da actividade antimicrobiana de diferentes extractos de larvas de Hermetia illucens para aplicação como ingrediente cosmético, Biomedical and Biopharmaceutical Research
  • 2020, Natural products as an important source in drug discovery, Current Pharmaceutical Design
  • 2020, Nanomedicine to target multidrug resistant tumors, Drug Resistance Updates
  • 2020, Insight the biological activities of selected abietane diterpenes isolated from plectranthus spp., Biomolecules
  • 2020, Further evidence of possible therapeutic uses of Sambucus nigra L. extracts by the assessment of the In Vitro and In Vivo anti-inflammatory properties of Its PLGA and PCL-Based Nanoformulations, Pharmaceutics
  • 2020, Design and synthesis of novel quinic acid derivatives: In vitro cytotoxicity and anticancer effect on glioblastoma, Future Medicinal Chemistry
  • 2020, Biofouling inhibition with grafted econea biocide: toward a nonreleasing eco-friendly multiresistant antifouling coating, ACS Sustainable Chemistry and Engineering
  • 2020, Antimycobacterial, antiplasmodial studies and cytotoxicity of oleanolic acid and its derivative from Syzygium aromaticum Linn (Myrtaceae),Estudos antiplasmódicos, antimicobacterianos e citotoxicidade do ácido oleanólico e do seu derivado da Syzygium aromaticum Linn (Myrtaceae), Biomedical and Biopharmaceutical Research
  • 2019-11-05, Development and Mechanistic Insight into the Enhanced Cytotoxic Potential of Parvifloron D Albumin Nanoparticles in EGFR-Overexpressing Pancreatic Cancer Cells, Cancers
  • 2019-10-16, An Evaluation of the DNA-Protective Effects of Extracts from Menyanthes trifoliata L. Plants Derived from In Vitro Culture Associated with Redox Balance and Other Biological Activities, Oxidative Medicine and Cellular Longevity
  • 2019-10, Parvifloron D from Plectranthus strigosus: Cytotoxicity Screening of Plectranthus spp. Extracts, Biomolecules
  • 2019-06, Determination of relevant endpoints to evaluate the in vivo barrier function in cutaneous health, Journal Biomedical and Biopharmaceutical Research
  • 2019-06, Cytotoxic effect of antioxidants found in food from plant origin on human osteosarcoma U2OS Cells, Journal Biomedical and Biopharmaceutical Research
  • 2019-05-02, Cytotoxic Activity of Royleanone Diterpenes from Plectranthus madagascariensis Benth, ACS Omega
  • 2019-05, Mg- and Mn-MOFs Boost the Antibiotic Activity of Nalidixic Acid, ACS Applied Bio Materials
  • 2019-05, Comparison Study of Different Extracts of Plectranthus madagascariensis, P. neochilus and the Rare P. porcatus (Lamiaceae): Chemical Characterization, Antioxidant, Antimicrobial and Cytotoxic Activities, Biomolecules
  • 2019, Naphthoylhydrazones: coordination to metal ions and biological screening, New Journal of Chemistry
  • 2019, In vitro assessment of antimicrobial, antioxidant, and cytotoxic properties of Saccharin-Tetrazolyl and-Thiadiazolyl derivatives: the simple dependence of the pH value on antimicrobial activity, Pharmaceuticals
  • 2019, Combination of hyaluronic acid and PLGA particles as hybrid systems for viscosupplementation in osteoarthritis, INTERNATIONAL JOURNAL OF PHARMACEUTICS
  • 2019, Abietane diterpenoids from Plectranthus spp. as lead protein kinase C modulators for cancer therapy, Basic & Clinical Pharmacology & Toxicology
  • 2019, A new Cu(II)-O-Carvacrotinate complex: Synthesis, characterization and biological activity, JOURNAL OF INORGANIC BIOCHEMISTRY
  • 2018-12, Screening of antioxidant and antimicrobial activities on Plectranthus spp. extracts, Journal Biomedical and Biopharmaceutical Research
  • 2018-12, Proceedings - CBiOS Science Sessions - 2018, Journal Biomedical and Biopharmaceutical Research
  • 2018-11-30, Aminobenzylated 4-Nitrophenols as Antibacterial Agents Obtained from 5-Nitrosalicylaldehyde through a Petasis Borono–Mannich Reaction, ACS Omega
  • 2018-11-13, Physicochemical, Antioxidant and Antimicrobial Properties of selected Portuguese Commercial Monofloral Honeys, Journal of Food and Nutrition Research
  • 2018-08-08, Mucoadhesive assessment of different antifungal nanoformulations, Bioinspiration & Biomimetics
  • 2018-06, Antitubercular and anti-inflammatory properties screening of natural products from Plectranthus species, Future Medicinal Chemistry
  • 2018-06, Anti-mycobacterial activity of labdane and halimane diterpenes obtained from Plectranthus ornatus Codd, Journal Biomedical and Biopharmaceutical Research
  • 2018-05, The teas of Portuguese centenarians, Free Radical Biology and Medicine
  • 2018-05, Mitochondrial dysfunction of halimane and labdane diterpenes in human lung cancer cells, Free Radical Biology and Medicine
  • 2018-05, Diterpenes from Plectranthus spp.: a ROS-induced cytotoxicity study, Free Radical Biology and Medicine
  • 2018-05, Anti-tumor properties of the redox-active compound Parvifloron D in breast cancer cells, Free Radical Biology and Medicine
  • 2018-04, Rosmarinus officinalis L.: an update review of its phytochemistry and biological activity, Future Science OA
  • 2018-03-13, Synthesizing a Berberine Derivative and Evaluating Antimicrobial Activity To Reinforce with Students the Potential Significance of Small Chemical Structure Changes for Biological Systems, Journal of Chemical Education
  • 2018-01, Discovery of a small-molecule protein kinase Cd-selective activator with promising application in colon cancer therapy, Cell Death & Disease
  • 2018, Vitis vinera L. pomace: chemical and nutritional characterization, Journal Biomedical and Biopharmaceutical Research
  • 2018, Screening of antioxidant and antimicrobial activities on Plectranthus spp. extracts, Journal Biomedical and Biopharmaceutical Research
  • 2018, Over-Expression of AtPAP1 Transcriptional Factor Enhances Phenolic Acid Production in Transgenic Roots of Leonurus sibiricus L. and Their Biological Activities, Molecular Biotechnology
  • 2018, Fluctuation in the assimilation of problematic experiences: a case study of dynamic systems analysis
  • 2018, Fluctuation in the assimilation of problematic experiences: a case study of dynamic systems analysis
  • 2018, Extraction Optimization and Structural and Thermal Characterization of the Antimicrobial Abietane 7a-Acetoxy-6ß-hydroxyroyleanone, Molecular Pharmaceutics
  • 2018, Development of a bioadhesive nanoformulation with Glycyrrhiza glabra L. extract against Candida albicans, BIOFOULING
  • 2018, Development of Parvifloron D-Loaded Smart Nanoparticles to Target Pancreatic Cancer, PHARMACEUTICS
  • 2018, Caracterização química e nutricional do bagaço de Vitis Vinera L.
  • 2018, Bioadhesive polymeric nanoparticles as strategy to improve the treatment of yeast infections in oral cavity: in-vitro and ex-vivo studies, European Polymer Journal
  • 2018, Anticancer properties of the abietane diterpene 6, 7-dehydroroyleanone obtained by optimized extraction, Future Medicinal Chemistry
  • 2018, Acetylcholinesterase Choline-Based Ionic Liquid Inhibitors: In Vitro and in Silico Molecular Docking Studies, ACS Omega
  • 2017-12, Cytotoxicity of N-nitrosoguanidines in a breast cancer cell model, Journal Biomedical and Biopharmaceutical Research
  • 2017-11-16, Antifouling Eco-Filters for Water Bio-Econtamination, Proceedings
  • 2017, Synthesis, antimicrobial activity and cytotoxic investigation of novel trifluoromethylated tetrazolo[1,5-a]pyrimidines, Medicinal Chemistry Research
  • 2017, Phytosomes as biocompatible carriers of natural drugs, Current Medicinal Chemistry
  • 2017, Past, recent progresses and future perspectives of nanotechnology applied to antifungal agents, Current Drug Metabolism
  • 2017, Pancreatic cancer therapy review: From classic therapeutic agents to modern nanotechnologies, Current Drug Metabolism
  • 2017, Nanotechnological strategies for nerve growth factor delivery: Therapeutic implications in Alzheimer's disease, Pharmacological Research
  • 2017, Nanosystems for skin delivery: From drugs to cosmetics, Current Drug Metabolism
  • 2017, Design of Finasteride-Loaded Nanoparticles for Potential Treatment of Alopecia, Skin Pharmacology and Physiology
  • 2017, Design and evaluation of novel topical formulation with olive oil as natural functional active, Pharmaceutical Development and Technology
  • 2017, Changes in symptom intensity and emotion valence during the process of assimilation of a problematic experience: a quantitative study of a good outcome case of cognitive-behavioral therapy
  • 2017, Broad overview of engineering of functional nanosystems for skin delivery, International Journal of Pharmaceutics
  • 2017, Antiparasitic Activity of Diterpenoids Against Trypanosoma cruzi, Planta Medica
  • 2017, Antibacterial, Anti-Inflammatory, Antioxidant, and Antiproliferative Properties of Essential Oils from Hairy and Normal Roots of Leonurus sibiricus L. And Their Chemical Composition, Oxidative Medicine and Cellular Longevity
  • 2017, An emerging integration between ionic liquids and nanotechnology: General uses and future prospects in drug delivery, Therapeutic Delivery
  • 2016-12, Xanthine Oxidase Inhibitory Activity of a Plectranthus saccatus aqueous extract, Journal Biomedical and Biopharmaceutical Research
  • 2016-12, Production of fermented Thai red glutinous rice using an isolated Monascus purpureus NART001 from commercially available Chinese red fermented rice, Journal Biomedical and Biopharmaceutical Research
  • 2016-11-01, Methyl 1,2-Orthoesters in Acid-Washed Molecular Sieves Mediated Glycosylations, ChemistrySelect
  • 2016-11-01, Choline-Based Ionic Liquids: Improvement of Antimicrobial Activity, ChemistrySelect
  • 2016, Unsaponifiable matter from oil of green coffee beans: cosmetic properties and safety evaluation, Drug Development and Industrial Pharmacy
  • 2016, The essential oils of rhaponticum carthamoides hairy roots and roots of soil-grown plants: Chemical composition and antimicrobial, anti-inflammatory, and antioxidant activities, Oxidative Medicine and Cellular Longevity
  • 2016, Reactivity of diterpenoid quinones: Royleanones, Current Pharmaceutical Design
  • 2016, N-H¿O and N-H¿Cl supported 1D chains of heterobimetallic CuII/NiII-SnIVcocrystals, Dalton Transactions
  • 2016, Multicomponent Petasis-borono Mannich Preparation of Alkylaminophenols and Antimicrobial Activity Studies, ChemMedChem
  • 2016, Lipoamino acid-based micelles as promising delivery vehicles for monomeric amphotericin B, International Journal of Pharmaceutics
  • 2016, Innovative formulation of nystatin particulate systems in toothpaste for candidiasis treatment, Pharmaceutical Development and Technology
  • 2016, Functionalized diterpene parvifloron D-loaded hybrid nanoparticles for targeted delivery in melanoma therapy, Therapeutic Delivery
  • 2016, Evaluating the impact of k-anonymization on the inference of interaction networks, Transactions on Data Privacy
  • 2016, EGF functionalized polymer-coated gold nanoparticles promote EGF photostability and EGFR internalization for photothermal therapy, PLoS ONE
  • 2016, Chemical composition and antimicrobial activity of essential oil of peruvian Dalea strobilacea Barneby, BOLETIN LATINOAMERICANO Y DEL CARIBE DE PLANTAS MEDICINALES Y AROMATICAS
  • 2016, Chemical composition and antimicrobial activity of essential oil of Peruvian dalea strobilacea barneby,Composición química y actividad antimicrobiana del aceite esencial de la planta Peruana Dalea strobilaceae Barneby, Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas
  • 2016, Changes in symptom intensity and emotion valence during the process of assimilation of a problematic experience: A quantitative study of a good outcome case of cognitive-behavioral therapy
  • 2016, Bioproduction of gold nanoparticles for photothermal therapy, Therapeutic Delivery
  • 2016, Bile acids and bile acid derivatives: use in drug delivery systems and as therapeutic agents, Expert Opinion on Drug Delivery
  • 2016, Antioxidant activity and rosmarinic acid content of ultrasound-assisted ethanolic extracts of medicinal plants, Measurement: Journal of the International Measurement Confederation
  • 2015-12, A novel topical association with zinc oxide, chamomile and aloe vera extracts - stability and safety studies, Journal Biomedical and Biopharmaceutical Research
  • 2015-10, Cytotoxicity screening of Plectranthus spp. extracts and individual components in MDA-MB-231 cells, Toxicology Letters
  • 2015-06, Antimicrobial screening of Plectranthus madagascariensis and P. neochilus extracts, Journal Biomedical and Biopharmaceutical Research
  • 2015, The abietane diterpenoid parvifloron D from Plectranthus ecklonii is a potent apoptotic inducer in human leukemia cells, Phytomedicine
  • 2015, Production and characterization of nanoparticles containing methanol extracts of Portuguese Lavenders, Measurement: Journal of the International Measurement Confederation
  • 2015, Polymeric nanoparticles modified with fatty acids encapsulating betamethasone for anti-inflammatory treatment, International Journal of Pharmaceutics
  • 2015, Plectranthus madagascariensis phytosomes: formulation optimization, Journal Biomedical and Biopharmaceutical Research
  • 2015, Lysozyme photochemistry as a function of temperature. the protective effect of nanoparticles on lysozyme photostability, PLoS ONE
  • 2015, Integrated approach in the assessment of skin compatibility of cosmetic formulations with green coffee oil, International Journal of Cosmetic Science
  • 2015, In vitro antioxidant properties of the diterpenes Parvifloron D and 7a-acetoxy-6ß- hydroxyroyleanone, Journal Biomedical and Biopharmaceutical Research
  • 2015, Hyperinsulinemia and hyperglycemia: risk factors for recurrence of benign paroxysmal positional vertigo
  • 2015, Hybrid nanoparticles for photodynamic and targeted cancer therapy: Cytotoxicity studies, Toxicology Letters
  • 2015, Good manufacturing practices for medicinal products for human use, Journal of Pharmacy and Bioallied Sciences
  • 2015, Antimicrobial screening of Plectranthus madagascariensis and P. neochilus extracts, Journal Biomedical and Biopharmaceutical Research
  • 2014-12, Synthesis of benzoazole ionic liquids and evaluation of their antimicrobial activity, Journal Biomedical and Biopharmaceutical Research
  • 2014-10, Antimicrobial screening of Plectranthus madagascariensis Benth. extracts, Planta Med
  • 2014-10, Abietane diterpenes from Plectranthus madagascariensis: A cytotoxicity screening, Planta Med
  • 2014, Production of extracts from preserved olives using supercritical CO2 and preliminary evaluation of its polyphenol content, Journal Biomedical and Biopharmaceutical Research
  • 2014, Optimization of the encapsulation efficiency of a novel oral insulin delivery nanosystem, Journal Biomedical and Biopharmaceutical Research
  • 2014, Optimization of medicinal plant extraction methods and their encapsulation through extrusion technology, Measurement: Journal of the International Measurement Confederation
  • 2014, Avaliação das propriedades sensoriais de uma formulação cosmética contendo óleo de café verde
  • 2014, Antimicrobial plant extracts encapsulated into polymeric beads for potential application on the skin, Polymers
  • 2014, A novel modified acrylic bone cement matrix. A step forward on antibiotic delivery against multiresistant bacteria responsible for prosthetic joint infections, Materials Science and Engineering: C
  • 2014, A didactic approach for quantification of diazepam tablets by UV spectrophotometry, Journal Biomedical and Biopharmaceutical Research
  • 2013-06, Evaluation of the sensory properties of a cosmetic formulation containing green coffee oi, Journal Biomedical and Biopharmaceutical Research
  • 2013-03, In vitro Antimicrobial Activity of Royleanone Derivatives Against Gram-Positive Bacterial Pathogens.
  • 2013, Safety of green coffee oil in cosmetic formulations: From in vitro to clinical studies, Toxicology Letters
  • 2013, Development and evaluation of a novel topical treatment for acne with azelaic acid-loaded nanoparticles, Microscopy and Microanalysis
  • 2013, Antiproliferative activity of abietane diterpenoids against human tumor cells, Journal of Natural Products
  • 2012-06, Evaluation of diterpenoids from P. ornatus as potential COX-1 inhibitors, Journal Biomedical and Biopharmaceutical Research
  • 2012-06, Evaluation of antioxidant and antimicrobial activities of green coffee oil in cosmetic formulations, Journal Biomedical and Biopharmaceutical Research
  • 2012, Evaluation of antioxidant and antimicrobial activities of green coffee oil in cosmetic formulations, Journal Biomedical and Biopharmaceutical Research
  • 2011, Antimicrobial Properties of Plectranthus ornatus Extracts, 11-acetoxyhalima-5, 13-dien-15-oic Acid Metabolite and its Derivatives, The Natural Products Journal
  • 2010, Two new diterpenoids from Plectranthus species
  • 2010, Two new diterpenoids from Plectranthus species
  • 2010, Antimycobacterial metabolites from Plectranthus. Royleanone derivatives against Mycobacterium tuberculosis strains, Chemistry and Biodiversity
  • 2010, An easy and stereoselective rearrangement of an abietane diterpenoid into a bioactive microstegiol derivative
  • 2009, Isopimarane diterpenoids from Aeollanthus rydingianus and their antimicrobial activity, Phytochemistry
  • 2009, Isopimarane diterpenoids from Aeollanthus rydingianus and their antimicrobial activity
  • 2008, Antimicrobial activity of 7a-acetoxy-6ß-hydroxyroyleanone 12-O-benzoyl esters, Planta Medica
  • 2007, Further diterpenoids from Plectranthus ornatus and P. grandidentatus, Biochemical Systematics and Ecology
  • 2007, Further diterpenoids from Plectranthus ornatus and P-grandidentatus
  • 2006, Abietanes from Plectranthus grandidentatus and P. hereroensis against methicillin- and vancomycin-resistant bacteria, Phytomedicine
  • 2005, Structural and spectral assignment of three forskolin-like diterpenoids isolated from Plectranthus ornatus, Magnetic Resonance in Chemistry
  • 2002, Neoclerodane and labdane diterpenoids from Plectranthus ornatus, Journal of Natural Products
  • 2002, Antimicrobial activity of the diterpene 7 a-acetoxy-6b-hidroxyroyleanone and its 6b-carbamoyl derivative
  • 1995, Inhibition of astaxanthin synthesis in the green alga, Haematococcus pluvialis, Photosynthesis: from Light to Biosphere, Vol Iv
  • 1992, Seasonal changes in some photosynthetic properties of Ceratonia siliqua (carob tree) leaves under natural conditions, Physiologia Plantarum

Tese / Dissertação

  • 2011, Doutoramento, Phytochemical study and biological activities of diterpenes and derivatives from Plectranthus species

Capítulo de livro

  • 2023, Terpenes: A hope for glioblastoma patients, New Insights Into Glioblastoma, Elsevier
  • 2022, Natural Products as a Tool to Design New anti-MDR Lead Molecules. , Natural Products as a Tool to Design New anti-MDR Lead Molecules, Frontiers Media SA.
  • 2021, Natural Products and Nanopharmaceuticals, Nanopharmaceuticals: Principles and Applications Vol. 2. Environmental Chemistry for a Sustainable World, , 47, Springer,, Springer, Cham
  • 2021, Grape Pomace: A Potential Ingredient for the Human Diet, Advances in Food Science, Vide Le
  • 2020, Lead molecules from natural products: Insight into tubercular targets, Studies in Natural Products Chemistry, Elsevier
  • 2017, Isolation and purification of carnosol from Salvia officinalis, Comprehensive Organic Chemistry Experiments for the Laboratory Classroom (COCELC)
  • 2016, Natural Products as Lead Protein Kinase C Modulators for Cancer Therapy, Studies in Natural Products Chemistry
  • 2015, Antimicrobial abietane diterpenoids against resistant bacteria and biofilms
  • 2013, Antimicrobial natural products from Plectranthus plants, Formatex Research Center; “Microbial pathogens and strategies for combating them: science, technology and education

Revisão de livro

  • Natural Products

Recurso online

  • 2020-05-28, Animated Poster in Annual CQE Meeting: Self-assembly nanoparticles of Plectranthus hadiensis diterpenoids, https://twitter.com/Eva_M_DM/status/1265024572631527425
  • 2020-05-28, Animated Poster in Annual CQE Meeting: Phytochemical study and derivatization of a cytotoxic royleanone from P. grandidentatus, https://twitter.com/Vera89733278/status/1265038955227086848
  • 2020-05-28, Animated Poster in Annual CQE Meeting: Abietane Diterpenoids from Plectranthus mutabilis Codd., https://twitter.com/Gently2016/status/1264886258804887552

Artigo em conferência

  • Unravelling an abietane diterpenoid with very promising chemotherapeutic potential against glioblastoma cells, 71st International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA)
  • The teas of Portuguese centenarians
  • Plectranthus diterpenes: A promising therapy for glioblastoma treatment, 71st International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA)
  • EACR23-0331 | Unraveling the chemotherapeutic potential of Royleanone, a natural drug lead, against glioblastoma, EACR 2023 Congress: Innovative Cancer Science
  • 56ASM-0241 | Parvifloron D-based therapy for glioblastoma: targeting tumor microenvironment with a natural drug lead, 56TH ANNUAL SCIENTIFIC MEETING
  • 2022-11-01, Royleanone Analogues from Plectranthus spp. Demonstrate P-gp Inhibition and PKC Modulation
  • 2022-11-01, Phytochemical and Bioactivity Studies from Plectranthus ecklonii†
  • 2017-10, Screening the dermatological potential of Plectranthus species components – antioxidant and inhibitory capacities over elastase, collagenase and tyrosinase
  • 2017-10, Anti-inflammatory and anti-tubercular properties screening of natural products from Plectranthus species
  • 2013, Raised Source Drain Metal Diffusion in Finfet

Resumo em conferência

  • 2023-11, P. Plectranthus aliciae: Biological activity of 6,7-dehydroroyleanone and derivatives, 9th International Electronic Conference on Medicinal Chemistry
  • 2023-09-14, Gut-Skin Axis - Effect of kefir , ESPEN Congress 2023
  • 2022-12, Phytochemical study and bioactivity assessment of extracts from Plectranthus ecklonii Benth, 70th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA)
  • 2022, Applicability of lipid extracts from Hermetia illucens larvae in antiageing cosmetic formulations, InnovDelivery'22
  • 2022, Antioxidant Essential Oils as Innovative Ingredients in Facial Masks, InnovDelivery'22
  • 2021-11-02, Inhibition of P-glycoprotein activity to overcome multidrug resistance in cancer with new diterpene royleanones from <em>Plectranthus</em> spp.
  • 2021, Antioxidant, antimicrobial activity and general toxicity of methanolic ultrasound-assisted Plectranthus spp. extracts and their potential use in dermocosmetics, Fascination of Plants Day Event
  • 2020-12, Natural Cytotoxic Diterpenoids as a Potential Source of Drug Leads for cancer Therapy
  • 2020-11-05, Self-assembly nanoparticles of 7a-acetoxy-6ß-hydroxyroyleanone isolated from <em>Plectranthus hadiensis</em>
  • 2020-11-05, Insight into P-glycoprotein activity of royleanones from <em>Plectranthus</em> spp.
  • 2020-11-05, Chemical Composition and Biological Activity of Diterpenoids from <em>Plectranthus mutabilis</em>
  • 2013, A selective activator of protein kinase Cdelta identified using yeast, FEBS EMBO

Poster em conferência

  • 2023-11-30, How does the natural compound 7a-acetoxy-6ß-hydroxyroyleanone (Roy) modulates glioblastoma cells autophagy?, Mitochondria in Aging, Cancer and Cell Death (MAC) 2023: A Gathering of Experts in Mitochondria Research
  • 2023-11-30, Cytotoxic profile of naturally occurring abietane diterpenoids in urothelial carcinoma cells, Mitochondria in Aging, Cancer and Cell Death (MAC) 2023: A Gathering of Experts in Mitochondria Research
  • 2023-11-10, Somaí Paradigm: Establishing Innovative Benchmarks in Medical Cannabis., V Jornadas CBIOS
  • 2023-11-10, Paranaphthalene scaffold exhibits agonist modulatory influence on alpha subunit of PGE2-Bound EP2-GS Complex: Unveiling the mechanistic uterotonic property of Harungana madagascariensis Lam. (Hypericaceae) stem, V Jornadas CBIOS
  • 2023-11-10, New bioactive extracts with potential skin application from marine waste, Jornadas CBIOS
  • 2023-11-10, Cleomiscosin B: A potent coumarinolignoid exhibits promising antagonist inhibition of phosphodiesterase-5: Rationale of usage Paullinia pinnata L. (Sapindaceae) in the management of erectile dysfunction, V Jornadas CBIOS
  • 2023-11-10, 3D-QSAR, pharmacophore modeling, and molecular docking for the identification of novel potential P-glycoprotein (P-gp) blockers, V Jornadas CBIOS
  • 2023-11-01, 7a-acetoxy-6ß-hydroxyroyleanone as lead compound: from extraction optimization to hybrid nanoparticles for breast cancer therapy, 9th International Electronic Conference on Medicinal Chemistry
  • 2023-10, Exploring cytotoxic abietane diterpenoids from the Plectranthus spp. as promising nanosystems for cancer therapy, PSE Meeting 2023: Natural Drug Discovery Current Approach and Future Perspectives
  • 2023-07-13, Exploring the inhibitory effects of Côa valley plant extracts on osteoclast differentiation: Chemical characterization and cytotoxicity, II Bio Natural - Bioactive Natural Compounds Research Meeting
  • 2023-07-13, Biological activity screening of plant oil for skincare applications, II Bio Natural - Bioactive Natural Compounds Research Meeting
  • 2023-07-05, Enhancing Dermocosmetic Potential: Exploring Methanolic Extracts from Plectranthus spp. and their Bioactivity, Encontro Ciência 2023
  • 2023-07-02, Medicinal Centauri Honey: a promising ingredient?, 71st International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA)
  • 2023-07-02, Biological activity of 6,7-dehydroroyleanonederivatives from Plectranthus aliciae, 71st International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA)
  • 2023-07, Selective antitumoral activity of Thymelaea lanuginosa (Lam.) Ceballos & C. Vicioso. extract, III Bio.Natural- Bioactive Natural Products Research Conference
  • 2023-07, Novel nanoformulations of royleanone diterpenoids from Plectranthus spp. for MDR cancers, Ciência 2023
  • 2023-07, New diterpenoid derivatives from Plectranthus spp. for breast cancer therapy through protein kinase a activation, XIII iMed.ULisboa Postgraduate Students Meeting
  • 2023-07, Breast Cancer Drug Discovery: From Plants to Nanosystems, Ciência 2023
  • 2023-06-12, Unraveling the chemotherapeutic potential of Royleanone, a natural drug lead, against glioblastoma, EACR 2023 Congress: Innovative Cancer Science
  • 2023-06, Cytotoxic semi-synthetic abietane diterpenoid for breast cancer therapy: form molecular docking to protein kinase a activation, XXVIII Encontro Nacional da SPQ
  • 2023-05-25, Hybrid azole conjugates as viable anticancer and antimicrobial agents: a preliminary biological evaluation, CQE Days 2023
  • 2023-05, New formulations with royleanone derivatives from Plectranthus spp. to inhibit P-glycoprotein activity, 71st International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA)
  • 2023-03-19, Natural cytotoxic royleanones as tools for promising nanosystems, 6th International Symposium on Medicinal and Aromatic Plants (6th SIPAM)
  • 2023-03-19, Hermetia illucens larvae: Lipidic extracts as potential ingredients for dermocosmetic applications, 6th International Symposium on Medicinal and Aromatic Plants (6th SIPAM)
  • 2023-03, Natural cytotoxic royleanones and Hermetia illucens as promising nano-assemblies conjugated, International symposium on medicinal and aromatic plants- SIPAM-6
  • 2022-11-11, The Portuguese Physiology Roadmap ¿ From molecules to the individual ¿ perspectives from CBIOS
  • 2022-11, Phytochemical and bioactivity studies from Plectranthus ecklonii Benth., 8th International Electronic Conference on Medicinal Chemistry
  • 2022-11, Extracts from Plectranthus spp. and evaluation of their ability to promote tissue protection, 2º Congresso Internacional de Fisiologia
  • 2022-08, Lipidic extracts from Hermetia illucens larvae as potential ingredients for dermocosmetic applications, 70th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA)
  • 2022-07, Phytochemical study of the stems of ultrasound-assisted acetonic extract from Plectranthus hadiensis, 13th iMed.ULisboa Postgraduate Students Meeting
  • 2022-07, Methanolic extracts from Plectranthus spp. and their biological activity for dermocosmetics uses, 5th Meeting of Colégio Química Universidade Lisboa - "Forging bonds"
  • 2022-07, Design of diterpenoids as therapeutic agents in breast cancer through protein kinase C modulation, 13th iMed.ULisboa Postgraduate Students Meeting
  • 2022-07, Biological activity study of Plectranthus spp. methanol extracts for dermocosmetics uses, 13th Postgraduate Students Meeting- iMed.ULisboa
  • 2022-06-30, Self-assembly nanoparticles of bioactive compounds isolated from Plectranthus spp., InnovDelivery 2022
  • 2022-06-29, Chemotherapeutic potential of a Royleanone compound as natural drug lead against glioblastoma cells, 5th Grant Period Annual Conference - COST STRATAGEM
  • 2022-06-01, Cytotoxic Activity of diterpenes from Plectranthus spp. for MDR cancer therapy, 5th Annual Meeting of CA17104 - New diagnostic and therapeutic tools against multidrug resistant tumors (STRATAGEM)
  • 2022-05, Study of photocatalytic and antimicrobial activity of new g-C3N4/TNW hybrid nanomaterials, CQE Days 2022
  • 2022-05, Royleanone ester derivatives from Plectranthus spp. demonstrate P-glycoprotein inhibition, 1st African Conference on Natural Products & Related Fields
  • 2022-05, Royleanone ester derivatives from Plectranthus spp. as P-gp inhibitors, Ciência 2022
  • 2022-05, Lipid extracts from Hermetia illucens larvae as innovative ingredients in cosmetic formulations, The First African Conference on Natural Products and Related Fields
  • 2022-05, Enzymatic inhibition of methanolic Plectranthus spp. Extracts with skin traditional use, The First African Conference on Natural Products and Related Fields
  • 2022-05, Antioxidant Essential Oils impregnated in Novel Gelatin-based film Masks, The First African Conference on Natural Products and Related Fields
  • 2022-03-11, Characterization of lipid extracts from Hermetia illucens larvae and assessment of their potential use in cosmetic formulations, Cosmetinnov 2022
  • 2022-03, Exploring the Reactivity of a natural diterpenoid to modulate protein kinase C isoforms, ACS Spring 2022
  • 2022, More Evidence on The Gut-Skin Axis Modulation by Kefir., 2nd International Meeting of the Portuguese Society of Physiology, Coimbra, Portugal
  • 2022, Kefir intake reduces the clinical severity in atopic dermatitis by improving epidermal ¿barrier¿., ISBS 2022 - World Congress on Biophysics and Imaging of the Skin, Berlin, Germany
  • 2021-11-23, Evaluation of the genetics underlying a putative acquisition of antimicrobial resistance to novel alkylaminophenols, Microbiotec 2021
  • 2021-11-22, Biological Activities of Methanolic Ultrasound-Assisted Plectranthus spp. , 33rd AICC Annual Conference: International Meeting on Cancer Metabolism
  • 2021-11-18, Novel masks impregnated with antioxidant essential oils, II Bio.Natural Virtual Conference
  • 2021-11-18, Medicinal Centauri Honey: chemical composition and antioxidant properties, II Bio.Natural Virtual Conference
  • 2021-11, Using lipids extracted from black soldier fly larvae for nanoparticles development - Preliminary studies., II Bio.Natural ¿ Bioactive Natural Products Research Meeting.
  • 2021-11, Phytochemical and bioactivity studies from Plectranthus hadiensis varieties, 7th International Electronic Conference on Medicinal Chemistry
  • 2021-11, Evaluation of the Lysyl Oxidase Like 2 (LOXL2) inhibitory activity of a natural pimarane and its sugar derivatives, II Bio.Natural-Bioactive Natural Products Research Meeting
  • 2021-09-10, New Ca(II)-nalidixic acid coordination towards surface engineering, 11th convention on Crystal Forms (CF@Bo11) - Walking the walk of polymorphs, co-crystals and solvates, Bologna, Italy (Virtual Event)
  • 2021-09-10, Disclosing the synthesis, characterization and antimicrobial activity of new silver(I)-tazobactam coordination frameworks, 11th convention on Crystal Forms (CF@Bo11) - Walking the walk of polymorphs, co-crystals and solvates, Bologna, Italy
  • 2021-07-09, Increased antibacterial properties of indoline-derived phenol Mannich bases, 31st ECCMID, European Congress of Clinical Microbology and Infectious diseases
  • 2021-06, Inhibition of p-glycoprotein activity to overcome multidrug resistance in cancer with new diterpene royleanones from Plectranthus spp., iMed.ULisboa Meeting 2021
  • 2021-05-27, Mechanosynthesis of pyrazinamide coordination frameworks to improve antitubercular therapy, CQE Days 2021 Spring Edition on Twitter (@cqedays, @cqe_lisboa, #CQEDays2021)
  • 2021-05-18, Natural diterpenoids from Plectranthus spp. as apoptotic agents, In Fascination of Plants Day Event
  • 2021-05-18, LOXL2 inhibitory activity of pimaranes from medicinal plants, conferência do Dia Internacional do Fascínio das Plantas
  • 2021-05-18, Atividade antioxidante, antimicrobiana e toxicidade geral de extratos metanólicos de Plectranthus spp. e o seu potencial na dermocosmética, Dia Internacional do Fascínio das Plantas
  • 2021-05-10, Atividade antimicrobiana de Extratos etanólicos de Plectranthus spp. e o seu potencial na cosmética, XXV COLAMIQC- VIRTUAL
  • 2021-05, Apoptosis in cancer cells induced by abietane diterpenoids from Plectranthus spp., ACS Spring 2021
  • 2021-02, Fluid bio-decontamination with biocidal ceramic filters, ISMOS-8 - 8th International Symposium on Applied Microbiology and Molecular Biology in Oil Systems
  • 2021, Variabilidade na função de barreira da pele de indivíduos saudáveis, induzida pela ingestão de kefir., XXV Congresso Latino-Americano e Ibérico de Quimicos Cosmeticos-COLAMIQC- I, Venezuela
  • 2020-12-15, Innovative nanosystems with natural cytotoxic royleanone diterpenes from Plectranthus spp., COST Action 17104 (STRATAGEM) WG2 Meeting and International Online Symposium on ¿Synthesis and nanodelivery strategies for new therapeutic tools against Multidrug Resistant Tumours¿- Online event
  • 2020-11-23, LOXL2 inhibitory activity of ultrasound aqueous extracts from medicinal plants, IV jornadas CBIOS
  • 2020-11, Royleanones from Plectranthus spp as P-glycoprotein inhibitors, Encontro Ciência 2020
  • 2020-11, Novel class of P-glycoprotein inhibitors from Plectranthus spp. , WG3 meeting and International Online Symposium on ¿New Therapeutic Tools Against Preclinical Models of Multidrug Resistant Tumors¿
  • 2020-10, Estudio fitoquímico de las partes aéreas de Plectranthus hadiensis (Forssk.) Schweinf. ex Sprenger (Translation: ¿Phytochemical study of the aerial parts of Plectranthus hadiensis (Forssk.) Schweinf. ex Sprenger¿), XII Congreso de Fitoterapia Ciudad de Oviedo
  • 2020-09, Abietane diterpenoids isolated from plectranthus spp. induce cancer cell death via apoptosis, in Virtual 7th EFMC Young Medicinal Chemists¿ Symposium (EFMC-YMCS Virtual Event 2020)
  • 2020-07, Natural Cytotoxic Diterpenoids, as Potential Drug Leads for cancer Therapy , Italian Young Medicinal Chemistry Virtual Meeting (I-YMC-VMEET)
  • 2020-07, Molecular Docking Studies of Promising P-Glycoprotein Inhibitors obtained from Plectranthus spp., Italian Young Medicinal Chemistry Virtual Meeting (I-YMC-VMEET)
  • 2020-03, Diterpenoids from edible Plectranthus spp. as potential chemopreventive and therapeutic agents in cancer, III Lusófona¿s Nutrition Meeting
  • 2020-02, Cytotoxic royleanones from Plectranthus madagascariensis as agents to overcome multidrug resistant in cancer, COST Action CA17104 STRATAGEM Annual Conference ¿ 3rd MC meeting and 4th WGs meetings
  • 2020-02, Activation of protein kinase C epsilon (PKCe) and delta (PKCd) inhibits chemokine secretion enhancing antitumoral effects of CXCR2 antagonist, COST Action CA17104 STRATAGEM Annual Conference ¿ 3rd MC meeting and 4th WGs meetings
  • 2020, Impact of kefir consumption on cutaneous health assessed using an SLS-induced lesion model. , 55th Annual Congress of SBFIS, Brasil
  • 2019-11, Molecular docking as a tool to design novel PKC-d modulators for colon cancer therapy , 2019 Sino-Portugal Forum on Traditional Medicine, Nanchang Jiangxi, China, November, 2019
  • 2019-10-25, Water bio-decontamination with non-release biocidal coated filters, 2nd International Meeting on New Strategies in Bioremediation Processes (BioRemid 2019)
  • 2019-10-10, Assessment of the impact of oral intake of the probiotic kefir in cutaneous health., Physioma 2019 - 1st International Meeting of the Portuguese Society of Physiology, Lisbon, Portugal
  • 2019-10, Abietane diterpenoids from Plectranthus spp. as a New Class of Protein Kinase C Modulators for Cancer Therapy, Physioma 2019
  • 2019-09-28, Antioxidant Properties and Toxicity of Portuguese Centenarians Herbal Teas , Bio.Natural Meeting 2019, CBIOS-ECTS, Universidade Lusófona, Auditório Agostinho da Silva, Lisboa.
  • 2019-09-27, P 59: Antioxidant properties and toxicity of Portuguese centenarians herbal teas, , Bioactive Natural Products Research Meeting, Bio.Natural 2019, Auditório Agostinho da Silva (ULHT), Book of Abstracts, p.96, 27-28 September, ULHT, Lisboa, Portugal
  • 2019-09-27, Antimicrobial fluid filtration on biocidal coated monoliths, I Bioactive Natural Products Research Meeting 2019 (Bio.Natural)
  • 2019-09, Isolation study of a bioactive diterpene from Plectranthus ornatos Codd., Bio.Natural
  • 2019-09, Isolation of Two Bioactive Diterpenes from Plectranthus mutabilis codd. , Bio.Natural
  • 2019-07-18, Cyclam-based agents for bio-decontamination, 4th Meeting of the CQUL (4ECQUL)
  • 2019-07, Structure-based drug design of royleanone derivatives from Plectranthus spp. as PKC-d modulators, , Natural Products in Drug Discovery and Human Health (NatProdDDH), Lisbon,
  • 2019-07, Optimizing natural royleanones from Plectranthus spp. to overcome multidrug resistance in cancer, in 4rd scientific meeting of CQUL - Chemistry: Shaping the Future & 2019 Summer School (4ECQUL)
  • 2019-07, Isolation and Biological activity study of coleon U from Plectranthus mutabilis Codd. , 4rd scientific meeting of CQUL - Chemistry: Shaping the Future & 2019 Summer School (4ECQUL)
  • 2019-07, Bioactivity of abietane diterpenoids from Plectranthus spp. against human cancer cells, Natural Products in Drug Discovery and Human Health (NatProdDDH)
  • 2019-07, Bio-guided Isolation and Biological activity study of Coleon U from Plectranthus mutabilis Codd. , Ciência 2019
  • 2019-05-18, Plectranthus species: A source of Anticancer lead molecules, Fascination of Plants Day Event: ¿Plants promoting healthy diet¿
  • 2019-05, Royleanone derivatives from Plectranthus spp. as new P-glycoprotein inhibitors, XXVI Encontro Nacional da SPQ
  • 2019-05, Royleanone Diterpenoids from Plectranthus spp. as P-glycoprotein inhibitors in multidrug resistant cells, XXVIème Congrès National de la SFBMEc
  • 2019-05, Anticancer lead molecules search from Plectranthus species, XXVIème Congrès National de la SFBMEc
  • 2018-12, Cytotoxic derivatives of 6,7-dehydroroyleanone and 7a-acetoxy-6ß-hydroxyroyleanone, 3rd Training School ¿Computational modeling tools in drug discovery with natural products¿
  • 2018-11-13, Antimicrobial monolithic filters for water bio-decontamination, 4th Workshop CATSUS
  • 2018-11, Hemi-síntese de carbamatos a partir do diterpeno natural 6,7-dehidroxroyleanona, 1ª Conferência sobre Investigação em Produtos Naturais e Avícolas ¿ Iniciativa conjunta CBIOS-CYTED
  • 2018-09-06, Bioactive functional biocides for water decontamination, 7th EuCheMS Conference on Nitrogen Ligands
  • 2018-08-26, Cytotoxicity of natural halimane and labdane diterpenes by mitochondrial dysfunction in human lung cancer cells, 66th Annual Meeting of GA jointly with 11th Shanghai International Conference on Traditional Chinese Medicine and Natural Medicine
  • 2018-08-26, Abietane diterpenoids from Plectranthus spp. induce ROS-mediated cytotoxicity, 66th Annual Meeting of GA jointly with 11th Shanghai International Conference on Traditional Chinese Medicine and Natural Medicine
  • 2018-06-04, Halimane and labdane diterpenoids from Plectranthus ornatus against Mycobacterium tuberculosis and human lung cancer cells, Ciência 2018
  • 2018-05-18, Extraction and isolation of cytotoxic 7a-acetoxy-6ß-hydroxyroyleanone from P. grandidentatus and in silico prediction of new derivatives, Fascination of Plants Day Event: ¿Plants promoting healthy diet¿
  • 2018-05-01, The dermatological potential of Plectranthus species against extracellular matrix enzymes and reactive oxygen species, . 2018 World Congress of the International Society for Biophysics and Imaging of the Skin
  • 2018-01-14, Optimization of production of nanostrutured lipid carriers by solvent-evaporation double emulsion technique for topical drug delivery, XII Spanish-Portuguese Conference on Controlled Drug Delivery
  • 2016-10-21, Roy-Bz: a new small-molecule selective activator of protein kinase Cd with anticancer activity., International Conference on Cancer Research and Targeted Therapy
  • 2016-05-31, Novel Antimicrobial Abietane Cationic Amphiphiles for Dermatological Applications, International Society for Biophysics and Imaging of the Skin
  • 2016-05-29, Synthesis and Efficacy of Abietane Cationic Amphiphiles from Dehydroabietic Acid, 6th International Congress of Aromatic and Medicinal Plants.
  • 2016-04-15, Antimicrobial Activity of Novel Abietanes Cationic Amphiphiles Alginate Microspheres, III Simpósio de Nanociência e Nanotecnologia Médica
  • 2015-12-01, Antimicrobial activity and biofilm formation inhibition of alginate microspheres of dehydroabietic acid., 11º Encontro Nacional de Química Orgânica/4º Encontro Nacional de Química terapêutica
  • 2015-09-24, Ácido desidroabiético: um agente natural antimicrobiano contra bactérias resistentes e biofilmes., 1a Jornadas Técnico-Científicas
  • 2015-07, Antimicrobial Activity and Toxicity Evaluation of Choline Analogues, 19th European Symposium on Organic Chemistry
  • 2013-02-13, Using yeast to search for new selective activators of protein kinase C isoforms., IJUP6th meeting of young researchers

Patente

  • ROY-BZ: A SMALL MOLECULE SELECTIVE ACTIVATOR OF PROTEIN KINASE CDELTA (PKCDELTA), WO/2017/134637, UNIVERSIDADE DO PORTO [PT]/[PT] COFAC- COOPERATIVA DE FORMAÇÃO E ANIMAÇÃO CULTURAL, CRL [PT]/[PT]
  • NANOSSISTEMA DE OURO COM REVESTIMENTO BIOPOLIMÉRICO E GAMA DE ABSORÇÃO NO INFRAVERMELHO PRÓXIMO E MÉTODO PARA A SUA PREPARAÇÃO, WO2017095251 , COFAC - COOPERATIVA DE FORMAÇÃO E ANIMAÇÃO CULTURAL [PT]/[PT] FACULDADE DE CIÊNCIAS DA UNIVERSIDADE DE LISBOA [PT]/[PT]
  • Espumas biocidas não lixiviantes com atividade anti-incrustante, processo para a sua produção e respetivos usos, INPI – 116986, 2

Outra produção

  • 2021, Plectranthus spp. and their secondary metabolites for dermatological disorders treatment
  • 2021, Increased antibacterial properties of indoline-derived phenolic Mannich bases, European journal of medicinal chemistry
  • 2021, Abietane Diterpenoids from Plectranthus spp. as a starting tool in Cancer Research
  • 2020-11-05, Updated review of the bioactive compounds isolated from <em>Plectranthus ecklonii </em>Benth
  • 2019-11-08, Abietane Diterpenoids from Plectranthus spp. as a potential new class of Protein Kinase C Modulators
  • 2019-11, Optimization extraction study for the isolation of a bioactive diterpene from Plectranthuns ornatus Codd.
  • 2019-10, Stilbenoids in Grapes and Wine, Handbook of Dietary Phytochemicals
  • 2019-10, Design and molecular docking studies of new potential PKC-d activators based on royleanone scaffold
  • 2019-10, Cytotoxic activity of coleon diterpenoids from Plectranthus mutabilis codd
  • 2019-10, Anticancer Hybrid Combinations with phenolic compounds
  • 2019-10, Acetylcholinesterase and antioxidant evaluation of C18-functionalized ferruginol analogues
  • 2019, Molecular docking as a tool to design new royleanone derivatives for colon cancer therapy based on PKC-d modulation
  • 2019, Bio-guided phytochemical study of Plectranthus mutabilis Codd.
  • 2018, Naturally Occurring Plectranthus-derived Diterpenes with Antitumoral Activities
  • 2018, Innovative nanotechnology formulations for the treatment of yeast infections in oral mucosa, Diretores de Tese: Catarina Pinto Reis, Patrícia Mendonça Rijo, Jesús Molpeceres. La candidiasis oral es una infección provocada por hongos oportunistas que generalmente afecta a personas con inmunodeficiencia, bien por una infección viral o por un síndrome asociado a otras causas. Sin embargo, en algunos casos pueden verse afectadas personas sanas. Aunque Candida albicans es el principal agente p
  • 2018, Gestão de resíduos hospitalares: estudo de referenciais de boas práticas, com base na perceção e na avaliação do risco de exposição ocupacional num hospital central, Diretores de Tese: Maria do Céu Costa, Ángel Asúnsolo del Barco. A natureza, diversidade e perigosidade dos resíduos hospitalares (RH) exige procedimentos especí¿cos na sua gestão. A necessidade de uma intervenção especi¿ca sobre os RH, é incontornável na sociedade atual, pelas exigências de Saúde Pública e Ambiental, e obriga a que as instituições de saúde integrem o processo de gestão de RH no s
  • 2018, Cytotoxic Natural Products as an Approach Towards the Development of Therapeutic Agents for Precision Medicine
  • 2017, Lamiaceae extracts and compounds for topical application through nano delivery systems, Diretores de Tese: Patrícia Rijo, Catarina Reis, Ana M. Díaz Lanza. La resistencia a los antibióticos es uno de los principales problemas de salud que afectan a todos los continentes, ya sean países desarrollados o en desarrollo. Este tipo de infección es responsable de un elevado número de víctimas, siendo una de las más importantes causas de muerte en todo el mundo, sin una forma efectiva de ter
  • 2016, Ligand-functionalized nanoparticles for targeted therapy of melanoma in situ, Diretores de Tese : Dra. Patrícia Rijo ; Dra. Catarina Reis ; Dr. Jesús Molpeceres. El melanoma cutáneo es un tipo de cáncer con origen en los melanocitos que se vuelven malignos. El tratamiento del melanoma cutáneo ha evolucionado mucho en los últimos treinta años, sin embargo, no ha conseguido incrementar significativamente la supervivencia de los pacientes con cáncer avanzado. Además, el tratam
  • 2016, Isolation, modeling and phytosome forms of antimicrobial and antiproliferative compounds from plectranthus spp., Diretores de Tese : Dra. Patrícia Rijo ; Dra. Catarina Reis ; Dra. Ana Mª Díaz-Lanza. Os produtos naturais têm sido uma valiosa fonte de novos produtos farmacêuticos. As plantas de género Plectranthus L'Her (Lamiaceae) possuem uma ampla diversidade de usos etnomedicinais, que correspondem a uma indicação da presença de potenciais fármacos na sua composição. Métodos inovadores para a veiculação dos
  • 2005, Definição e Modelação Hidráulica do Controlo por Montante à Distância numa Rede de Canais com Reservatórios Associados, O controlo por jusante à distância em canais de distribuição de água permite uma resposta eficiente e automática às variações de caudal ao nível dos utentes. A profundidade controlada é a da secção mais a jusante de cada um dos trechos de canal considerado. O órgão de controlo é a comporta de admissão ao mesmo trecho, o que permite alguma antecipação na acção de controlo e, consequentemente, uma m

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