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Presentation
Presentation
Veterinary pharmacology is an experimental science dealing with the properties of drugs and their effects on living systems. It includes the study of the sources of drugs (pharmacognosy), magnitude and time course of the observed pharmacological effect on the body pharmacodynamics, the relationship between administered doses and the observed biological fluid/tissue concentrations and time in the body pharmacokinetics, use in the treatment of diseases, and toxicity. The drugs include any chemical agent (other than food) used in the treatment, cure, prevention or diagnosis of disease, or the control of physiological processes. Clinical pharmacology in the veterinary setting is the clinical discipline devoted to the optimal use of drugs in veterinary patients, maximizing their prophylactic or therapeutic benefits while ensuring that adverse consequences are minimized. Nowadays, veterinary pharmacology and toxicology are disciplines contributing to the paradigm "One World, One Health"
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Class from course
Class from course
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Degree | Semesters | ECTS
Degree | Semesters | ECTS
Bachelor; Master Degree | Semestral | 4
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Year | Nature | Language
Year | Nature | Language
3 | Mandatory | Português
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Code
Code
ULHT478-8522
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Prerequisites and corequisites
Prerequisites and corequisites
Not applicable
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Professional Internship
Professional Internship
Não
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Syllabus
Syllabus
Pharmacokinetics: Concepts of Absorption, bioavailability, distribution, bioequivalence, biotransformation and drug excretion. Dosage and dosage adjustment.
Pharmacodynamics: Dose-effect curves. Potency versus Efficacy. Competitive and non-competitive antagonism. Regulatory proteins and components of chemical signaling mechanisms. Variation in pharmacological response. Clinical selectivity.
Endocrine System. Thyroid hormones and antithyroid drugs. Glucocorticoids, mineralocorticoids. Reproduction hormones.
Nervous System: Anticholinergics. Tranquillizers, analgesics and anesthetics. Anticonvulsants and analeptic agents.
Respiratory System: Typical, expectorants, mucolytics, bronchodilators Non-steroidal anti-inflammatory drugs and and antipyretics.
Digestive system: Appetite stimulants, emetics and antiemetics. Modelers of gastric and intestinal motility. Gastrointestinal protectors..Pharmaceutical forms.
Routes of administration.Veterinary prescription.
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Objectives
Objectives
1. Students will be able to acquire knowledge about the fundamentals and general concepts of drug development, from its origin to its use in veterinary clinical practice, as well as experimental
methodologies to support that development.
2. Acquire knowledge on Pharmacokinetics and Pharmacodynamics and the ability to relate both concepts.
3. Students will be able to understand the mechanisms of action, the pharmacological effects, the adverse reactions, and major therapeutic indications of the different groups of drugs.
4. Students will be able to construct working knowledge in the areas of pharmacotechnics, pharmacography with regard to the administration of drugs, in small animal clinics.
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Teaching methodologies and assessment
Teaching methodologies and assessment
Innovative methodologies will be employed to support the teaching-learning process.
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References
References
Riviere, J.E , Papich, Mark G (2018) Veterinary Pharmacology and Therapeutics. 8th Ed. Iowa State University Press. Ames. Katsung, B.G (2009) Basic & Clinical Pharmacology . 11 th Ed. McGraw-Hill.
Spinosa, H. S., Górniak, S. L. e Bernardi, M. M. (2011) Farmacologia Aplicada à Medicina Veterinária . 4aEd. Guanabara/Koogan.
Prista, L, Alves, C. e Morgado, R (1979). Técnica Farmacêutica e Farmácia Galénica . Vols I, II e III. 2a Ed. Fundação Calouste Gulbenkian. Lisboa.
APIFARMA (2007) Simposium Veterinário - Medicamentos e produtos de saúde animal .
Boothe, D. (2011). Small Animal Clinical Pharmacology and Therapeutics, 1a Ed., W. B. Saunders Company.Prescott, J.F., Baggot, D. & Walker, D. (2000). Antimicrobial Therapy in Veterinary Medicine. Iowa State Press.
Baggot, D. (2001) The Physiological Basis of Veterinary Clinical Pharmacology. 1a Ed., WileyBlackwell.
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Office Hours
Office Hours
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Mobility
Mobility
No
