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Presentation
Presentation
The UC intends to interpret and draw structures of organic molecules, correlating its name (common, IUPAC) with its structure. Correlate the structure and functionality of a compound with its family, its reactivity and its physical properties. Write, interpret and apply the mechanisms associated with the transformations of the main functional groups and interpret and assign structures of low complexity organic compounds, through the joint use of various structural elucidation methods (microanalysis, FT-IR, NMR, MS) applying these techniques. natural products and their applications in the areas of Health, Food and Environment.
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Class from course
Class from course
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Degree | Semesters | ECTS
Degree | Semesters | ECTS
Bachelor | Semestral | 5
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Year | Nature | Language
Year | Nature | Language
2 | Mandatory | Português
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Code
Code
ULHT2710-5805
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Prerequisites and corequisites
Prerequisites and corequisites
Not applicable
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Professional Internship
Professional Internship
Não
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Syllabus
Syllabus
1-Introdution: Natural products, Classes, history and applications in health, pharmaceuticals. 2-Identification using Spectroscopic and spectrometric techniques for structural analysis: NMR spectrometry techniques (1H, 13C). Infrared Spectroscopy (FT-IR). Mass spectrometry); 3- Addition reactions in alkenes and alkynes, addition-elimination in aldehydes, ketones, carboxylic acids and derivatives, amines and electrophilic substitution in aromatics; 4- The carbonyl group: properties, synthesis and reactivity, Carboxylic acids and derivatives, properties, synthesis and reactivity. .Amines: properties, synthesis and reactivity. 5.Aromaticity. Aromatic electrophilic substitution; 6-Applications: Synthesis of biologically active pharmacological compounds from plants. Classifications of natural products. Natural products derived from amino acids. Alkaloids. Carbohydrates. Flavonoids, polyphenols.
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Objectives
Objectives
Acquire a global perspective of the study of Chemistry of natural products, basic knowledge, scientific methods to apply in the laboratory or in industry in specific areas such as pharmaceutical, Environment, Food, Health and its interaction with other sciences. Develop observation, reasoning and logic in solving problems and drawing conclusions. Prepare students in the knowledge and handling of extraction material in the laboratory following the rules of risk and safety. Allow students to distinguish natural organic molecules extracted from plants, microorganisms and synthetic molecules as well as to relate their structures to their biological reactivity with the joint use of various methods of structural clarification (microanalysis, FT-IR, NMR, MS).
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Teaching methodologies and assessment
Teaching methodologies and assessment
Implementation of extra classes online for student support with additional exercises for homework giving better understanding of the subject.
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References
References
- 1-Solomons, T.W.G, Fryhle, C.B, Snyder S.A., "Organic Chemistry", 12 th Edition, Wiley, 2016.
- 2- K. P. Volhardt, N.E. Schore, W.E. Organic Chemistry, Freeman and Company, 6Ed, 2010.
- 3- R. Morrison, R. Boyd, Quimica Orgânica, Fundação Calouste Gulbenkian, 11 edição, 2011.
- 4-P. M. Dewick "Medicinal Natural Products" A Biosynthetic Approachg,, Wiley, Chichester, 2009.
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Office Hours
Office Hours
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Mobility
Mobility
No
