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Presentation
Presentation
This UC introduces the constitution, structure and funcion of the cell as a functional unit but also as part of multicelular organisms.
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Class from course
Class from course
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Degree | Semesters | ECTS
Degree | Semesters | ECTS
Bachelor | Semestral | 5.5
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Year | Nature | Language
Year | Nature | Language
1 | Mandatory | Português
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Code
Code
ULHT1101-944
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Prerequisites and corequisites
Prerequisites and corequisites
Not applicable
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Professional Internship
Professional Internship
Não
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Syllabus
Syllabus
The cell Cell theory Chemical composition Prokaryotic and eukaryotic cells Transport mechanisms Organelles and cellular structures ¿ structure/function relationship Biological membranes Nucleus ER, RER and Golgi complex Mitochondria Chloroplast Cytoskeleton ECM Intercellular communication and adhesion Cell-cell and cell-substrate adhesion Signalling pathways Genome Central dogma of Biology Different condensation states of chromatin Prokaryotic versus eukaryotic genome Gene Replication, transcription and translation DNA replication mechanism, replication fork, DNA polymerases Transcription mechanism, RNA polymerases Transcript processing Genetic code tRNAs and ribosome Polypeptide chain production Gene expression regulation Why regulate gene expression? Cell differentiation Cell cycle Mitosis and meiosis Cell cycle control Apoptosis
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Objectives
Objectives
After attending this CU, the student should know the structure and function of different cell types and their elements, and understand the basic mechanisms that allow cells to function as an independent unit or as part of a larger organism. The student should comprehend the relation between cell (and cellular elements) structure and function, as well as cellular regulation mechanisms. The student should also understand the mechanisms involved in the storage, usage and transmission of genetic information. The laboratory classes allow students to manipulate and analyse cells and their components. Autonomy, organization, responsibility, bibliography research and group cooperation are promoted in the laboratory and during the elaboration of an oral presentation.
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Teaching methodologies
Teaching methodologies
Active learning methodologies based on the resolution of practical problems, on the exposition by the students of some concepts addressed in laboratory classes and the use of observations/results obtained in the laboratory as a starting point for the discussion of more complex concepts/topics.
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References
References
Lodish, H et al. (2021), Molecular Cell Biology, 9th Ed, W. H. Freeman and Co. (Informação complementar online: http://bcs.whfreeman.com/lodish7e/#t_800911____) Reece, J. B, Urry, L. A., Cain, L. C., Wasserman, S. A., Minorsky, P. V., Jackson, R.B., (2016) Campbell Biology, 11th ed., Pearson Education, Inc. Campos, L.S. (2008); Entender a Bioquímica, 5ªed. Escolar Editora.
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Assessment
Assessment
Descrição
Data limite
Ponderação
Frequência 1
35%
Frequência 2
35%
Apresentação de trabalho
15%
Aprovação na UC requer uma classificação mínima de 9,5 valores.
A) Regime de avaliação contínua – nota final resulta da média ponderada dos seguintes componentes:
- Dois testes escritos abrangendo toda a matéria leccionada nas aulas teóricas e laboratoriais (componentes T1 e T2) – 35% x2 - um mínimo de 9 valores de nota média destes dois componentes é requerida para aprovação à UC
- Desempenho nas aulas laboratoriais – 15% (A)
- Apresentação (+ discussão) de trabalho – 15%(B)
Nota Final = T1(35%) + T2(35%) + A(15%) B(15%)
B) Regime de exame e exame de melhoria
- Prova escrita englobando a totalidade dos conteúdos programáticos, lecionados.
- O exame de melhoria de nota decorre em prova oral em época de recurso, englobando a totalidade dos conteúdos programáticos.
Evaluation: a minimum of 9.5 values is required for approval to the CU
A) Continuous evaluation – including the following components:
- Two written tests – 35% x2 (T1 e T2) – a minimum average of 9 values is required for approval to the CU
- Practical classes performance – 15% (A)
- Essay presentation and discussion o – 15% (B)
Final grade = T1(35%) + T2(35%) + A(15%) B(15%)
B) Exam and grade improvement exam
- Final written exam covering all the topics lectured on both lectures and practical classes.
- Improvement exam: oral exam covering all the topics lectured on both lectures and practical classes.
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Mobility
Mobility
Yes
