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Presentation
Presentation
Study of the basic principles of drug development from natural products and their role in drug development and production.
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Class from course
Class from course
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Degree | Semesters | ECTS
Degree | Semesters | ECTS
Bachelor; Master Degree | Semestral | 5
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Year | Nature | Language
Year | Nature | Language
3 | Mandatory | Português
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Code
Code
ULHT477-17211
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Prerequisites and corequisites
Prerequisites and corequisites
Not applicable
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Professional Internship
Professional Internship
Não
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Syllabus
Syllabus
1.1. Natural Products Derived from Acetate (continuation): Terpenes and Steroids. 1.2. Amino acids. 1.3. Natural Products Derived from amino acids (Peptides and Proteins. Proteolytic Enzymes. Non-ribossomal Polypeptides. Cyanogenic Glycosides and Glucosinolates). 1.4. Alkaloids (General aspects. Amino alkaloids. Pyridine and piperidine alkaloids. Tropane alkaloids. Pyrrolizidine alkaloids. Quinolizidine alkaloids. Bisbenzylisoquinoline alkaloids. Isoquinoline, terpenoid tetrahydroisoquinoline and quinoline alkaloids. Benzophenanthridine alkaloids. Indole alkaloids. Imidazole alkaloids. Steroidal alkaloids. Aconitum alkaloids) 1.5. Purines. 2. Phytotherapy and Use.
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Objectives
Objectives
In the Pharmacognosy and Phytotherapy II course unit it is intended that the student knows to: explain the basic principles of drug development from natural products and the role of natural products in the development and production of drugs. Know the biosynthesis and chemical structure division and characterization of bioactive natural products, especially from plants. identify a selection of the most important medicinal plants, explain their uses and account for their pharmaceutically active compounds. Use of Phytotherapy.
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Teaching methodologies
Teaching methodologies
The course adopts innovative methodologies to enhance the teaching-learning process. The theoretical and laboratory classes are designed to deepen students' knowledge and provide practical application of the learned concepts. The teaching materials and interactive resources are available on the Moodle platform. Additionally, the course includes a fieldwork component with a visit to an industry that uses natural products, integrated into the profession contact week. The presentation and discussion of scientific articles and written works on phytotherapy, followed by the use of gamification, promote critical analysis and a deeper understanding of the topics. These methodologies ensure that students effectively integrate theory and practice.
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References
References
Samuelsson, G., & Bohlin, L. (2009). Drugs of natural origin: A treatise of pharmacognosy (6th rev. ed.). Stockholm, Sweden: Apotekarsocieteten. Bruneton, J. (1999). Pharmacognosy, phytochemistry, medicinal plants (2nd ed.). Paris: Editions TEC & DOC Evans, W., & Evans, D. (2009). Trease and Evans' pharmacognosy (16th ed.). Edinburgh: WB Saunders.
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Assessment
Assessment
Aulas magistrais e laboratoriais, para aprofundar conhecimentos. Avaliações orais complementares da avaliação escrita. O aluno trabalhador-estudante que optar pela avaliação contínua deverá cumprir com os requisitos desta. A avaliação por exame final aplica-se aos alunos que por ele optem abrangendo a totalidade dos conteúdos programáticos (exame escrito e exame laboratorial). A melhoria de nota é realizada por avaliação escrita, englobando a totalidade dos conteúdos programáticos. Nesta UC inclui-se ainda um trabalho de campo que está integrado na semana de contacto com a profissão na forma de uma visita de estudo. Avaliação contínua: Assiduidade e desempenho 10% (A); um teste escrito (teste das aulas teóricas e teste laboratorial)30% (B); trabalhos laboratoriais, incluindo mini-projecto, 20% (C); apresentação e discussão de artigos científicos, 10% (D); apresentação e discussão de trabalhos escritos de fitoterapia, 30% (E).
Classificação final = A (10%) + B (30%) + C (20%) + D (10%) + E (30%).
Para obter aproveitamento, é obrigatória uma nota média mínima de 7,0 valores no teste escrito que inclui teste laboratorial.
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Mobility
Mobility
No
