Teacher
Marina Martins Badenes

Graus

• Mestrado
  Veterinary medicine
• Ensino secundário
  Scienfic field
• Doutoramento
  PhD in Veterinary sciences, specialty of Biomedical and Biological sciences (Reference “SFRH / BD / 61125 / 2009”)

Publicações

Journal article

• 2024-03-07, RHBDL4-triggered downregulation of COPII adaptor protein TMED7 suppresses TLR4-mediated inflammatory signaling, Nature Communications
• 2023-07, Semaphorin 4B is an ADAM17-cleaved adipokine that inhibits adipocyte differentiation and thermogenesis, Molecular Metabolism
• 2023-04, The ADAM17 sheddase complex regulator iTAP/Frmd8 modulates inflammation and tumor growth, Life Science Alliance
• 2020-06-04, Crosstalk between metabolism and immunity: the 3rd Annual Research Symposium of Instituto Gulbenkian de Ciência, The FEBS Journal
• 2020-01, Deletion of iRhom2 protects against diet-induced obesity by increasing thermogenesis, Molecular Metabolism
• 2019-10-29, iRhom2 and TNF: Partners or enemies?, Science Signaling
• 2017, Phosphorylation of iRhom2 Controls Stimulated Proteolytic Shedding by the Metalloprotease ADAM17/TACE, Cell Reports
• 2017, Delta-like 4/Notch signaling promotes ApcMin/+ tumor initiation through angiogenic and non-angiogenic related mechanisms, BMC Cancer
• 2015, Immune response profile elicited by the model antigen ovalbumin expressed in fusion with the bacterial OprI lipoprotein, Molecular Immunology
• 2012, Low-Dosage inhibition of DLL4 signaling promotes wound healing by inducing functional Neo-Angiogenesis, PLoS ONE
• 2010, Combination of Dll4/Notch and Ephrin-B2/EphB4 targeted therapy is highly effective in disrupting tumor angiogenesis, BMC Cancer

Thesis / Dissertation

• 2016, PhD, In vivo evaluation of the role of Delta-like 4/Notch signaling in the development of intestinal tumors
• 2009, Degree, Avaliação da função de DII4 na neoangiogénese tumoral e fisiológica

Conference poster

• 2020-03-02, Endothelial Dll4 is a multifactorial regulator of tumor metastization, EACR-AACR Basic and Translational Research Conference in partnership with ASPIC: Tumor Microevironment
• 2019-10-07, Endothelial Dll4 loss-of-function reduces metastasis through multiple mechanisms, 2nd EACR-MRS Conference on Seed and Soil: Mechanisms of Metastasis
• 2018-11-16, Metastasis is impaired by endothelial-specific Dll4 loss-of-function through inhibition of epithelial-to-mesenchymal transition, reduction of cancer stem cells and tumour cell intravasation, Exploring the boundaries of animal, veterinary and biomedical sciences. CIISA Congress 2018