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Presentation
Presentation
Clinical Biochemistry will focus on the relationship between biochemical processes at the cellular level and the physiological processes that occur in mammals (more specifically in the human body), focusing on examples of altered biochemical processes in human diseases. In this sense, the student will have an integrated view of the various metabolic pathways and their regulation, with a greater emphasis on clinical correlations, which describe aberrant biochemical states in disease states (with biochemical and genetic detail), learning that biochemical parameters should be analyzed and monitored. This unit will have an important practical component where the student will use methodologies and analyze parameters used in a clinical laboratory, in order to develop the critical spirit, and the coherent form of presentation of results, which is fundamental in any professional area.
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Class from course
Class from course
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Degree | Semesters | ECTS
Degree | Semesters | ECTS
Bachelor | Semestral | 5
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Year | Nature | Language
Year | Nature | Language
1 | Mandatory | Português
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Code
Code
ULHT7037-4623
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Prerequisites and corequisites
Prerequisites and corequisites
Not applicable
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Professional Internship
Professional Internship
Não
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Syllabus
Syllabus
1 - Introduction to Clinical Biochemistry 2 - Methods used in Clinical Biochemistry. 3 - Quality Control in Clinical Biochemistry. 4 - Laboratory evaluation of the carbohydrate. 5 - Laboratory evaluation of the lipids. 6 - Laboratory evaluation of kidney function. 7 - Laboratory evaluation of liver function. 8 - Laboratory evaluation of pancreatic function. 9 - Laboratory evaluation of cardiac function. 10 - Laboratory evaluation of proteins. 11 - Chemical and cytological analysis of urine
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Objectives
Objectives
Understand, in a comprehensive way, the fundamental biochemical mechanisms and their dysfunctions Identify the type and how to obtain the biological product needed to determine each biochemical parameter To know the analytical methods that can be applied in the quantitative and / or qualitative determination of a metabolite Apply learn current analytical techniques and platforms that are routinely used in clinical biochemistry and research To know and apply the biochemical mechanisms necessary for the interpretation of clinical results Understanding the implications of analytical and non-analytical errors Understand the principles of quality control
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Teaching methodologies
Teaching methodologies
Active learning methodologies based on the resolution of practical problems, on the exposition by the students of some concepts addressed in laboratory classes and the use of observations/results obtained in the laboratory as a starting point for the discussion of more complex concepts/topics.
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References
References
Devlin, Thomas. Textbook of Chemistry with Clinical Correlations. 7th Ed., Wiley 2010. ISBN-13: 978-0470281734 Burtis, C., Ashwood, E.-Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics 8th Ed, Philadelphia, W.B.Saunders Company, 2018. ISBN-13: 978-0323530446
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Assessment
Assessment
Avaliação contínua:
a) Pontualidade, participação em atividades propostas, capacidade de análise e discussão dos temas expostos, e desempenho nas aulas práticas/laboratoriais.
b) Preparação de mini-relatórios dos trabalhos laboratoriais e exercícios práticos.
c) Discussão dos trabalhos laboratoriais (Avaliação Oral).
d) Realização de 2 provas escritas sobre os conteúdos lecionados nas aulas teóricas e práticas/laboratoriais.
Nota final = a (5%) + b (25%) + c (10%) + d (2 x 30 %)Observações: As ferramentas de inteligência artificial (IA) utilizadas na realização dos elementos da alinea B), têm de ser reveladas pelos alunos, identificando o propósito para a sua utilização. Na avaliação destes elementos de avaliação, os resultados serão aferidos através de elemento de avaliação complementar (oral) com a ponderação de 10% (anilea C).
Avaliação por Exame Escrito: O aluno só será avaliado à componente que reprovou em avaliação contínua (teórica x ou prática y). O aluno será aprovado caso obtenha uma nota final igual ou superior a 9,5 val. A ponderação será de [x (60 %) + y (40 %)].
Melhoria de nota só poderá ser realizada por exame oral, em época de recurso e recai sobre todos os contéudos programáticos
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Mobility
Mobility
Yes
