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Class General Biochemistry

  • Presentation

    Presentation

    Biochemistry is a science that deals with the study of the chemical processes relevant to living organisms. This CU is fundamental for understanding the chemistry of food and the study of nutrition and nutrition.
  • Code

    Code

    ULHT1101-3476
  • Syllabus

    Syllabus

    I - Introduction to Biochemistry. Biochemistry and its objectives. Origin of life. The cell - a fundamental unit of biochemical processes. Organic chemistry with interest in Biochemistry Nomenclature in Organic Chemistry Chirality and Biological Activity II - The water. Properties of water. Acids, bases and buffers. Amino acids and proteins. III - The amino acids. The peptide bond. Structural levels of proteins. Active and regulatory centers. Myoglobin and hemoglobin. The enzymes. IV - Lipids. Definition and classification of lipids. The biological membranes. V - Glícidos. Definition and vocabulary. Classification and properties. VI - Biological information. Composition and primary structure of nucleic acids. Three-dimensional structure of DNA. Three-dimensional structure of the various RNAs.
  • Objectives

    Objectives

    The General Biochemistry aims to introduce students to the study of biochemical processes In this UC will be studied the structures of various biomolecules: proteins, carbohydrates, lipids and nucleic acids and the role of water in biochemistry. At the end of the course, students should master perfectly the bases that will allow the approach to metabolism and its changes that will be addressed in the following curricular units. Skills: knowledge and understanding of the structure and properties of the main classes of biomolecules (carbohydrates, lipids, proteins and nucleic acids) and the understanding of water functions as a solvent and his interactions with biomolecules. Students should also have an understanding of basic methodologies such as preparation of reagent solutions, potentiometry and acid-base determinations, spectrophotometry and determination of solution concentrations, extraction and purification of biomolecules and chromatography.
  • Teaching methodologies

    Teaching methodologies

    Active learning methodologies will be used in the General Biochemistry course unit, including Problem-Based Learning (PBL), gamification activities, and quizzes conducted both in the classroom and through the Moodle platform. These strategies will make it possible to monitor students' knowledge progression throughout the semester, consolidate the course content, and promote participation, motivation, and critical thinking.
  • References

    References

    Voet, D. & Voet. J.G. Biochemistry, (4th Ed). New York: John Wiley & Sons. (2010) Halpern M, Freire A, Quintas A. Bioquímica Organização Molecular da Vida. Lidel (2008) Berg, J.M. et al. Biochemistry (7th Ed). New York: Freeman and Company. (2010) Devlin T. Textbook of biochemistry; with clinical correlations. (7th Ed). Blucher (2011) Weil, J.H. Bioquímica Geral (2ª Ed). Lisboa: Fundação Calouste Gulbenkian. (2000)    
  • Assessment

    Assessment

    Avaliação contínua:

    A - Participação e desempenho nas aulas (10%)

    B- Testes escrito da componente oral e prática (60 %)

    C - Apresentação de trabalhos (15 %)

    D - Relatórios praticos (15%)

     

    Exame
    Exame final incide sobre a totalidade dos conteúdos programáticos, engloba uma prova escrita dda componente teórica e prática. .

    Melhoria
    Prova de avaliação oral, englobando a totalidade dos conteúdos programáticos, lecionados quer nas aulas teóricas quer nas laboratoriais.

     

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