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Presentation
Presentation
Cell Biology II is part of the fundamental biological sciences and provides students with knowledge of biological diversity, the mechanisms of energy acquisition and utilization in living organisms, the structural and functional organization of plant and animal organisms, classical genetics, and the main techniques used in Cell Biology. The course also addresses biodiversity as a source of bioactive compounds of pharmaceutical interest, highlighting the importance of natural resources in the discovery and development of new medicines. This course unit contributes to the consolidation of the scientific foundations required to understand biological processes relevant to Pharmaceutical Sciences, establishing the link between fundamental biological knowledge and its application in areas such as pharmacognosy, biotechnology, biomedical research, drug discovery and development, and pharmaceutical practice.
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Class from course
Class from course
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Degree | Semesters | ECTS
Degree | Semesters | ECTS
Bachelor; Master Degree | Semestral | 4
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Year | Nature | Language
Year | Nature | Language
1 | Mandatory | Português
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Code
Code
ULHT477-3077
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Prerequisites and corequisites
Prerequisites and corequisites
Not applicable
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Professional Internship
Professional Internship
Não
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Syllabus
Syllabus
1 Biological Diversity Viruses and prions The three domains of life 2 Plant Biology Photosynthesis and cellular respiration Plant histology Plant development and organ specialization Plant systematics and taxonomy; evolution and biological diversity; dichotomous keys and floras Comparative anatomy, morphology, life cycles, and ecology of botanically and pharmacologically relevant plant families 3 Biological Diversity as a Source of Pharmaceutical Products Natural resources as sources of novel bioactive molecules Primary metabolites and the main biosynthetic pathways of secondary metabolites Traditional medicine, isolation and purification of natural products, and innovative approaches to the discovery of new drugs 4 Animal Biology Structure and function Biological diversity: different forms, common challenges 5 Cell Biology Techniques Cell culture; Microscopy; Flow cytometry; Cell fractionation 6 Genetics Mendel's laws of inheritance
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Objectives
Objectives
Upon completion of this course unit, students will recognize biological diversity as a source of bioactive molecules with pharmaceutical interest, especially from plants. They will understand the value of natural resources in drug discovery and identify key primary metabolites and biosynthetic pathways of secondary metabolites. Students will gain knowledge of essential processes such as respiration, photosynthesis, and plant and animal development. They will describe the structure and function of major biological groups and apply Mendelian genetics to pedigree analysis. In the lab, students will develop skills in microscopy, Gram staining, pigment extraction, viability testing, chromatography, and cell counting. The course promotes autonomy, critical thinking, and the ability to apply theoretical and experimental knowledge in pharmaceutical sciences.
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Teaching methodologies
Teaching methodologies
The course unit adopts innovative methodologies that promote active learning and critical thinking, emphasizing the integration of theoretical and practical knowledge. In addition to laboratory sessions that develop essential technical skills, students engage in creative seminars that challenge them to apply cellular biology concepts to real-world pharmaceutical contexts and communicate science to diverse audiences. These activities include the creation of science communication campaigns or case studies on the cellular effects of pharmacological treatments, fostering scientific literacy, creativity, and communication skills. Digital tools and interactive platforms are also used to support continuous learning, encouraging autonomy and peer collaboration.
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References
References
Alberts, B., Bray, D., Hopkin, K., Johnson, A., Lewis, J., Raff, M., Roberts, K., & Walter, P. (2017). Fundamentos da biologia celular (4.ª ed.). Artmed. Campbell, N. A., Urry, L. A., Cain, M. L., Wasserman, S. A., Minorsky, P. V., Jackson, R. B., & Reece, J. B. (2021). Campbell biology (12th ed.). Pearson. Campos, L. S. (2009). Entender a bioquímica (5.ª ed.). Escolar Editora. Lodish, H., Berk, A., Kaiser, C. A., Krieger, M., Bretscher, A., Ploegh, H., Amon, A., & Scott, M. P. (2021). Molecular cell biology (9th ed.). W. H. Freeman.
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Assessment
Assessment
A aprovação na unidade curricular requer uma classificação final mínima de 9,5 valores (escala de 0-20).
A) Avaliação contínua
A classificação final é obtida através da média ponderada dos seguintes elementos de avaliação:
Classificação Final = 0,35 × F1 + 0,35 × F2 + 0,15 × S + 0,15 × P
em que:
F1 (35%) - 1.ª frequência, incidindo sobre os conteúdos lecionados até à data, incluindo as componentes teórica, teórico-prática e laboratorial;
F2 (35%) - 2.ª frequência, incidindo sobre os restantes conteúdos da unidade curricular, incluindo as componentes teórica, teórico-prática e laboratorial;
S (20%) - Seminário em grupo, subordinado a um dos temas propostos (Células Sob Tratamento: Estudo de Caso Criativo ou A Farmácia Dentro da Célula: Campanha de Divulgação), avaliado através do suporte digital (5%) e da apresentação oral e discussão (15%);
P (10%) - Participação, assiduidade e desempenho nas aulas teórico-práticas e laboratoriais.Para aprovação em avaliação contínua, os estudantes devem:
- obter uma média mínima de 8,50 valores nas duas frequências (F1 + F2)/2
- obter uma classificação final igual ou superior a 9,5 valores.
B) Exame Final e Exame de Recurso
O exame consiste numa prova escrita abrangendo a totalidade dos conteúdos programáticos das componentes teórica, teórico-prática e laboratorial.
A aprovação requer uma classificação mínima de 9,5 valores.C) Melhoria de Classificação
A melhoria de classificação é realizada através de exame oral sobre a totalidade dos conteúdos programáticos da unidade curricular.
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Mobility
Mobility
No
