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Presentation
Presentation
Biochemistry is an interdisciplinary science that involves an interrelationship between basic disciplines such as chemistry and biology. Biochemistry has a very important role in several areas, particularly in the Food and Pharmaceutical Industries, in the Environment, in the various aspects of Toxicology and in the Health area.
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Class from course
Class from course
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Degree | Semesters | ECTS
Degree | Semesters | ECTS
Bachelor; Master Degree | Semestral | 4
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Year | Nature | Language
Year | Nature | Language
1 | Mandatory | Português
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Code
Code
ULHT477-33
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Prerequisites and corequisites
Prerequisites and corequisites
Not applicable
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Professional Internship
Professional Internship
Não
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Syllabus
Syllabus
Introduction to Biochemistry Biochemistry and its objectives Origin of life The water Water properties Acids, bases and buffers Amino acids and proteins The peptide bond Structural levels of proteins Active and regulatory centers Myoglobin and hemoglobin The enzymes Lipids Structure of lipids Definition and classification of lipids Biological membranes Carbohydrates Definition and vocabulary Ranking Introduction to bioenergetics The principles of thermodynamics The free energy of Gibbs ATP – production and hydrolysis Biological information Composition and primary structure of nucleic acids Three-dimensional structure of DNA Three-dimensional structure of the various RNAs
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Objectives
Objectives
The discipline of Biochemistry I aims to define the concept of biochemical reaction, introduce students to the different actors of biochemistry (water and biomolecules) and introduce the great biochemical functions such as the functioning of enzymes, bioenergetics and biological information. Students should know and understand the structure and properties of the major classes of biomolecules (carbohydrates, lipids, amino acids and proteins and nucleic acids) and their interactions with the solvent water. Capacity in basic methodology in the scope of Biochemistry (realization of reagent solutions, colorimetry, calibrations, spectrophotometry). At the conclusion of the course, students should master the bases that will allow them to approach the curricular unit of Biochemistry II.
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Teaching methodologies
Teaching methodologies
Knowledge progression tests throughout the semester are prepared at home through the learning platforms. Pedagogical games are used in the classroom to capture students’ attention and motivate learning. Inverse learning, in which the student prepares the lessons under the teacher’s guidance; at the end, students evaluate their peers and perform a self-assessment to stimulate knowledge and self-criticism.
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References
References
Voet, D. & Voet. J.G. Biochemistry (4ª Ed.). New York: John Wiley & Sons. 2010 Halpern M, Freire A, Quintas A. Bioquímica Organização Molecular da Vida. Lidel. 2008 Berg, J.M. et al. Biochemistry (7ª Ed.). New York: Freeman and Company. 2010 Devlin T. Textbook of biochemistry; with clinical correlations (7ª Ed.). Blucher. 2011 Weil, J.H. Bioquímica Geral (2ª Ed.). Lisboa: Fundação Calouste Gulbenkian. 2000
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Assessment
Assessment
Avaliação contínua ao longo do semestre com componente teórica (A) com uma ponderação de 60% e com componente prática laboratorial (B) com uma ponderação de 40%.
Componente Descrição Ponderação A Teste escrito de avaliação contínua de conhecimentos teóricos e práticos
Apresentação e discussão de trabalhos escritos
30 %
30 %
B Apresentação e discussão de cadernos de laboratório
Apresentação oral de trabalhos práticos
Desempanho e participação nas aulas práticas
20 %
10 %
10%
Para obter aproveitamento, é obrigatória uma nota média mínima de 7,0 valores, no teste escrito que inclui teste laboratorial. O aluno trabalhador-estudante que optar pela avaliação contínua deverá cumprir com os requisitos acima definidos.
A avaliação por exame final aplica-se aos alunos que por ele optem abrangendo a totalidade dos conteúdos programáticos (exame escrito e exame laboratorial).
A melhoria de nota é realizada sob a forma de prova de avaliação oral, englobando a totalidade dos conteúdos programáticos.
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Mobility
Mobility
No
