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Presentation
Presentation
Introduction to Physical Chemistry aims to provide students with the knowledge necessary to understand the importance of physical processes in biochemistry. Biological systems have some constraints imposed by their environment. This course aims to identify and understand the constraints that physics and chemistry impose on biological systems.
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Class from course
Class from course
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Degree | Semesters | ECTS
Degree | Semesters | ECTS
Bachelor | Semestral | 5.5
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Year | Nature | Language
Year | Nature | Language
1 | Mandatory | Português
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Code
Code
ULHT2532-16914
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Prerequisites and corequisites
Prerequisites and corequisites
Not applicable
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Professional Internship
Professional Internship
Não
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Syllabus
Syllabus
1.Gases 1.1.Perfect gases 1.1.1.Gases laws. 1.2. Real Gases. 1.2.1.Molecular interactions. 1.2.2.van der Waals Equation. 1.3. Environmental impact. Mitigating enzymes. 2.Thermodynamics. 2.1. First law. 2.1.1.Internal energy, worl and heat. 2.1.2.Reversible versus irreversible processes. 2.1.3. Enthalpy. 2.1.4 Hess law, Enthalpy of formation 2.1.5.Heat Capacity. 2.2. Second law of thermodynamics. Entropy 2.3. Third law of Thermodynamics 2.3.1. Reaction Entropy. Gibbs energy. 2.4. Chemical equiibrium. Changes in Gibbs energy. 2.4.1.Equilibrium constant. van't Hoff Equation. 3. Electrochemistry. 3.1.Standard Reduction PotentialPotencial. 3.2.Nernst equation; equilibrium constant determination. 4. Kinetics. 4.1.Reaction rates.Reaction order. 4.2.Integrated rate laws. 4.4. Steady-sate. 4.5. Enzimatic catalysis. Arrhenius equation.
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Objectives
Objectives
This course aims to understand the limits imposed by physics and chemistry on biological systems. Students will have studied thermodynamics to understand the energy requirements of chemical processes, chemical equilibrium, and chemical and biochemical kinetics, including catalysis and electrochemistry. Students will be able to determine kinetic parameters, identify reaction mechanisms and factors that influence catalysis. They will also be able to determine thermodynamic parameters related to the stability of biomolecules such as proteins or DNA
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Teaching methodologies
Teaching methodologies
In this CU, students carry out individual and group work in order to work as a team. Practical classes are very intertwined with theoretical classes so that students understand the importance of Physical-Chemistry in understanding biological systems.
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References
References
Paula, J. and Atkins, P. (2010), Atkins' Physical Chemistry, 9 edition, Oxford edition Paula, J. and Atkins, P. (2006), Physical Chemistry for the Life Sciences, 2 edition, W.H. Freeman and Company
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Assessment
Assessment
1.Avaliação contínua:
Componente laboratorial: (Frequência obrigatória de 2/3 das aulas laboratoriais)
A classificação laboratorial é a media poderada de três componentes: desempenho e assiduidade do
aluno no laboratório (15%), questionários (40%), um relatório e discussão (45%)- A classificação da
prática deve ser maior ou igual a 9,5 .
Componente teórica: A classificação é a média dos resultados obtidos nas duas frequências teóricas
(50% cada). A classificação teórica deve ser maior ou igual a 9,5.
Classificação final: Media ponderada: componente prática 40%, componente teórica, 60%.
2.Época de recurso: Classificação final, media ponderada: 40% da avaliação da componente prática e 60% da
componente teórica (exame).
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Mobility
Mobility
No
