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Presentation
Presentation
Structural biochemistry allows the acquisition of theoretical knowledge and practical skills for the structural identification of sample chemical species from the variation of a certain property. This curricular unit focuses on instrumental analysis methodologies such as x-ray diffraction, nuclear magnetic resonance and electron microscopy.
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Class from course
Class from course
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Degree | Semesters | ECTS
Degree | Semesters | ECTS
Bachelor | Semestral | 5.5
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Year | Nature | Language
Year | Nature | Language
3 | Mandatory | Português
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Code
Code
ULHT2532-16918
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Prerequisites and corequisites
Prerequisites and corequisites
Not applicable
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Professional Internship
Professional Internship
Não
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Syllabus
Syllabus
- Concepts about the structure of proteins, nucleic acids and supramolecular biological complexes such as protein-binding, protein-protein, protein-nucleic acid;
- Interpretation of the structure-function relationship of proteins.
- Main techniques for determining biological structures such as X-ray diffraction, multidimensional NMR spectroscopy, electron microscopy, techniques for interpretation and validation of experimental results
- Conceptual and analytical understanding of the structure-function relationship of biological macromolecules.
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Objectives
Objectives
Introduce and develop basic concepts, addressing the main instrumental methodologies of structural analysis of interest in the field of biochemistry. Highlighting the basic principles of instrumental and structural analysis, as well as its applicability and selection criteria. To approach the theoretical foundations of methods, equipment and characteristics of use and analysis through the techniques and methods of x-ray diffraction, nuclear magnetic resonance and electronic microscopy. These fundamentals allow the acquisition of skills for performing chemical analysis, making it possible to identify similarities and differences between the methodologies, as well as to define strategies for minimizing potential interferences in the analysis. The practices allow the development of technical skills fundamental to the execution of the analytical methods in question.
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Teaching methodologies and assessment
Teaching methodologies and assessment
The innovative methodologies to support the teaching-learning process used are essentially: Project Based Learning; Flipped Classroom; Design Thinking.
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References
References
- [Preencher APELIDO], [Preencher Primeiros Nomes] - [Preencher Título]. [Preencher Edição. Local de publicação :Editor, Ano de publicação. Descrição física. Série. ISBN)]
- [Preencher APELIDO], [Preencher Primeiros Nomes] - [Preencher Título]. [Preencher Edição. Local de publicação :Editor, Ano de publicação. Descrição física. Série. ISBN)
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Office Hours
Office Hours
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Mobility
Mobility
No
