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Presentation
Presentation
The CU of Metabolism and Bioenergetics introduces the concept of metabolism and the main metabolic pathways. In particular a large part of the classes will be dedicated to the description of aerobic metabolism and associated pathways. By the end of the CU, the students should possess a clear knowledge of biochemical processes sustaining living organisms.
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Class from course
Class from course
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Degree | Semesters | ECTS
Degree | Semesters | ECTS
Bachelor | Semestral | 5.5
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Year | Nature | Language
Year | Nature | Language
2 | Mandatory | Português
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Code
Code
ULHT2532-11607
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Prerequisites and corequisites
Prerequisites and corequisites
Not applicable
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Professional Internship
Professional Internship
Não
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Syllabus
Syllabus
1. Introduction to metabolism (Metabolism, anabolism, catabolism. Source of energy and redox reactions. Categories of metabolism. Metabolism and evolution.). 2. Aerobic metabolism (Digestion and absorption of glicids. Glycolysis. Fermentations associated to glycolysis. Glycogenogenesis and glycogenolysis. Gluconeogenesis. Krebs cycle. Pentose-phosphate cycle. Oxidative phosphorylation. Regulation.). 3. Photosynthesis (Light phase of photosynthesis (2 photosystems). ¿Dark phase¿.). 4. Lipid metabolism (Digestion, absorption and transport. Beta-oxidation of fatty acids. Biosynthesis of fatty acids. Cholesterol metabolism.). 5. Aminoacid metabolism (Protein digestion. Transamination and deamination of aminoacids. Urea cycle. Cetoacid catabolism. Biosynthesis of aminoacids.). 6.Transmembrane transport (Non mediated transport. Passive mediated transport. Active mediated transport using ATP. Active mediated transport using an ionic gradient.).
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Objectives
Objectives
Competences that should be developped: Knowledge and understanding of main metabolic pathways that are responsible for the production of cell energy and of biosynthesis pathways for most biomolecules, including aspects of evolutive relationships between different kinds of metabolism. Strengthening the students¿ abilities in techniques used in Biochemistry (preparation of reagent solutions, colorimetry, diferent techniques of liquid chromatography, calibration, spectrophotometry, extraction and purification of biomolecules like proteins and polysaccharides, electrophoresis, enzyme kinetics, database mining).
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Teaching methodologies
Teaching methodologies
Laboratory and practical training is a very important component of the Cycle of Studies, essential to ensure the quality of student training. The practical skills and laboratory autonomy of graduate students are recognized by the other institutions where they continue their studies.
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References
References
- Voet, D. & Voet, J.G. (2010). Biochemistry. 4th Ed. John Wiley & Sons, New York. - Stryer, L. (1995). Biochemistry. 4th Ed. Freeman and Company, New York. - Weil, J.H. (2000). Bioquímica Geral. 2ª Ed. Fundação Calouste Gulbenkian, Lisboa.
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Assessment
Assessment
Descrição
Data limite
Ponderação
Avaliação prática (preparação das aulas, desempenho, caderno)
dd-mm-yyyy
50%
Avaliação teórica (2 frequências + recuperação facultativa)
dd-mm-yyyy
50%
(...)
Ensino presencial com aulas teóricas e laboratoriais: As aulas teóricas são aulas
com frequência voluntária seguindo o programa definido e de acordo com os objectivos da UC. As aulas
laboratoriais presenciais são aulas tutoradas, orientadas por um docente, destinadas a aplicar as
técnicas mais comuns em Bioquímica.
Requisitos para aproveitamento final:
1) Avaliação contínua:
- Frequência obrigatória de 2/3 das aulas laboratoriais.
- Classificação prática igual ou superior a 9,5 valores (avaliação contínua do desempenho dos alunos, 50
% na classificação final).
- Duas frequências ao longo do semestre 50% (média igual ou superior a 9,5 valores).
2) Exame final:
- Exame com 2 componentes: prática (50%) e teórica (50%).
- Nota igual ou superior a 9,5 valores à cada componente.
- Isenção de repetir um dos elementos da avaliação em caso de nota igual ou superior a 9,5 valores
obtida para este em avaliação contínua ou exame final anterior.Contact teaching with theoretical and laboratory classes: Theoretical classes are
lectures of facultative attendance that follow the defined syllabus and respect the objectives of the CU.
Presential laboratory classes are under the guidance and orientation of a teacher and are intended to
practice the most frequent techniques in Biochemistry.
Requirements to pass the discipline:
1) Continuous evaluation:
-Attendance at 2/3 of laboratory classes.
-Laboratory classification > or = 9,5 (continuous evaluation of student's work, 50% final classification).
-Two midterm exams during the semester with a 50% weight (average > or = 9,5).
2) Final examination:
- Examination with 2 components: practical (50%) and theoretical (50%).
- Classification > or = 9,5 for each component.
- Students with a classification > or = 9,5 obtained for an element of a previous evaluation (continuous
evaluation or previous examination) are exempted from repeating it.
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Mobility
Mobility
Yes
