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Presentation
Presentation
Learning about the fundamental aspects of Toxicology in general and its various applications, particu larly in the field of food, environment and health.Ability to understand the mechanisms of cellular and tissue toxicity associated with toxic agents through food or the environment and the action of drugs. Know how to identify the type of contaminant and its toxic effects. Clarify the mechanism (s) of toxicity. Assess adverse effects on human health from exposure to contaminants.
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Class from course
Class from course
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Degree | Semesters | ECTS
Degree | Semesters | ECTS
Bachelor | Semestral | 5
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Year | Nature | Language
Year | Nature | Language
3 | Optional | Português
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Code
Code
ULHT6643-17177
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Prerequisites and corequisites
Prerequisites and corequisites
Not applicable
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Professional Internship
Professional Internship
Não
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Syllabus
Syllabus
General Toxicology Considerations. Introduction to Toxicology Applications of Toxicology : food toxicology, ecotoxicology, analytical toxicology and clinical toxicology. Toxicity Types: Acute, Subacute, Subchronic and Chronic Toxicity. Factors Affecting Toxicity.Toxicity to organs and sys tems Mechanisms of toxicity. Genetic toxicology and carcinogenicity.Short-term tests Contaminants and toxins present in food.Toxins in food. Heavy metal contamination: mercury, iron and cadmium . Dioxins: their formation and contamination in foods intended for human consumption Biotransformation of carcinogens present in food: natural or formed during food processing Contaminants and environmental toxicants:Air Pollutants, soil and water. Aquatic and terrestrial ecotoxicology. Toxicology applied to Biotechnology.
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Objectives
Objectives
Basic knowledge about toxicology, and effects of toxic substances (eg pollutants, drugs, toxins) in humans and ecossystems. The meaning of bioconcentration, biodegradation and bioamplification in human body and in the environment. Concepts of the procedures involved in the classification of chemicals and risk assessment. The student will be able to learn the key concepts of toxicology. Identify the various pollutants in the environmental compartments air, soil, water. Interpret dose-response curves. Identify the potential toxic substances to human health security. Know the main toxicology testing and its application to specific case study
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Teaching methodologies
Teaching methodologies
Within the scope of the curricular unit, videos and documents are made available on moodle to support the subject. These documents and didactic material allow the visualization of programmatic contents and facilitate the learning of the basic concepts necessary to achieve the objectives stipulated for the chair. Whenever possible, field trips are made to reinforce the syllabus and whenever possible the collection of samples to be used in the practical work of students in the laboratory.
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References
References
1-Casarett e Doulls (2001). Toxicologia. A ciência dos tóxicos. Tradução Portuguesa. Compêndio. McGraw Hill. Lisboa. 2-Colin Baird (1998) Environmental Chemistry. 2 Ed. W.H.Freeman & Co. nd 3-C.H.Walker, S.P. Hopkins, R.M. Sibly and D.R. Peakall (2000). Principles of Ecotoxicology. 2 Ed.T a y l o r & F r a n c i s . L o n d o n
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Assessment
Assessment
Descrição: Teorica: 50% - Média dos dois testes ou um teste Global final com toda a matéria. Parte prática 50% - Composta por 3 relátorios (trabalho escrito 40% + discussão 60%) correspondendo a 30% da nota e um poster cientifico, correspondendo a 20% da nota (49% elaboração do poster + 51% discussão do poster). Aprovação com 9,5 valores a cada uma das partes ( teórica e prática).
Falhando a provação em avaliação contínua, o aluno submete-se a exame, aprovação com 9,5 valores
Description: Theory: 50% - Average of the two tests or a final comprehensive test covering all the material. Practical part 50% - Consisting of 3 reports (written work 40% + discussion 60%) corresponding to 30% of the grade and a scientific poster, corresponding to 20% of the grade (49% poster preparation + 51% poster discussion). Passing grade of 9.5 for each part (theoretical and practical).
If the student fails the continuous assessment, they must take an exam, passing with a grade of 9.5
Descrição
Data limite
Ponderação
2 Testes de avaliação teoricos / teste Global
28-01-2024
50%
Poster cientifico + discussão
28-01-2024
20%
3 Relatórios práticos + discussão 28-01-2024 30%
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Mobility
Mobility
No
