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Presentation
Presentation
The CU of Biomolecules aims to define the concept of biochemical reaction, to present the different actors of Biochemistry, water and biomolecules, to the students, and to introduce the main biochemical functions, like enzyme mechanisms, bioenergetics, biological information. By the end of this CU the students should master perfectly these fundamentals that will allow the transition to the CU of Metabolism and Bioenergetics.
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Class from course
Class from course
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Degree | Semesters | ECTS
Degree | Semesters | ECTS
Bachelor | Semestral | 5.5
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Year | Nature | Language
Year | Nature | Language
1 | Mandatory | Português
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Code
Code
ULHT2532-16551
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Prerequisites and corequisites
Prerequisites and corequisites
Not applicable
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Professional Internship
Professional Internship
Não
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Syllabus
Syllabus
1. Introduction to Biochemistry (1.1. Biochemistry and its objectives. 1.2. Origin of Life. 1.3. The cell ¿ fundamental unit of biochemical processes.). 2. Water (2.1. Properties of water. 2.2. Acids, bases and buffers.). 3. Aminoacids and proteins (3.1. Aminoacids. 3.2. The peptide bond. 3.3. Structure levels of proteins. 3.4. Active centers and regulation centers. 3.5. Myoglobin and hemoglobin. 3.6. Enzymes.). 4. Lipids (4.1. Definition and classification of lipids. 4.2. Biological membranes.). 5. Glicids (5.1. Definition and vocabulary. 5.2. Classification.). 6. Introduction to Bioenergetics (6.1. The principles of thermodynamics. 6.2. Gibbs free energy. 6.3. ATP ¿ production and hydrolysis.). 7. Biological information (7.1. Composition and primary structure of nucleic acids. 7.2. 3D structure of DNA. 7.3. 3D structure of various RNAs.).
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Objectives
Objectives
Knowledge and understanding of the structure and properties of the main classes of biomolecules (glicids, lipids, aminoacids and proteins, nucleic acids) and of their interactions with the solvent water. Abilities in basic methodology in the area of Biochemistry (preparation of reagent solutions, colorimetry, liquid chromatography, solid phase chromatography, calibration, spectrophotometry, extraction and purification of biomolecules, electrophoresis, enzyme kinetics, database mining).
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Teaching methodologies
Teaching methodologies
Laboratory and practical training is a very important component of the Cycle of Studies, essential to ensure the quality of student training. The practical skills and laboratory autonomy of graduate students are recognized by the other institutions where they continue their studies.
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References
References
Voet, D. & Voet, J.G. (2010). Biochemistry. 4th Ed. John Wiley & Sons, New York. Stryer, L. (1995). Biochemistry. 4th Ed. Freeman and Company, New York. Weil, J.H. (2000). Bioquímica Geral. 2ª Ed. Fundação Calouste Gulbenkian, Lisboa.
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Assessment
Assessment
Descrição
Data limite
Ponderação
Avaliação prática (preparação das aulas, desempenho, caderno)
dd-mm-yyyy
50%
Avaliação teórica (2 frequências + recuperação facultativa)
dd-mm-yyyy
50%
(...)
Ensino presencial com aulas teóricas e laboratoriais: As aulas teóricas são aulas
com frequência voluntária seguindo o programa definido e de acordo com os objectivos da UC. As aulas
laboratoriais presenciais são aulas tutoradas, orientadas por um docente, destinadas a aplicar as
técnicas mais comuns em Bioquímica.
Requisitos para aproveitamento final:
1) Avaliação contínua:
- Frequência obrigatória de 2/3 das aulas laboratoriais.
- Classificação prática igual ou superior a 9,5 valores (avaliação contínua do desempenho dos alunos, 50
% na classificação final).
- Duas frequências ao longo do semestre 50% (média igual ou superior a 9,5 valores).
2) Exame final:
- Exame com 2 componentes: prática (50%) e teórica (50%).
- Nota igual ou superior a 9,5 valores à cada componente.
- Isenção de repetir um dos elementos da avaliação em caso de nota igual ou superior a 9,5 valores
obtida para este em avaliação contínua ou exame final anterior.Contact teaching with theoretical and laboratory classes: Theoretical classes are
lectures of facultative attendance that follow the defined syllabus and respect the objectives of the CU.
Presential laboratory classes are under the guidance and orientation of a teacher and are intended to
practice the most frequent techniques in Biochemistry.
Requirements to pass the discipline:
1) Continuous evaluation:
-Attendance at 2/3 of laboratory classes.
-Laboratory classification > or = 9,5 (continuous evaluation of student's work, 50% final classification).
-Two midterm exams during the semester with a 50% weight (average > or = 9,5).
2) Final examination:
- Examination with 2 components: practical (50%) and theoretical (50%).
- Classification > or = 9,5 for each component.
- Students with a classification > or = 9,5 obtained for an element of a previous evaluation (continuous
evaluation or previous examination) are exempted from repeating it.
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Mobility
Mobility
Yes
